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Back in the RACE: (Re)defining the role of radiation therapy in liver and gallbladder cancers
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Date
2025-08-13
Authors
Barry, Aisling S.
Ashman, Jonathan B.
Jethwa, Krishan R.
Kim, Hyun
Miller, Eric D.
Tao, Randa
Wojcieszynski, Andrzej P.
Chuong, Michael D.
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier Inc.
Published Version
Abstract
This Oncology Scan focuses on expanding the role of radiation therapy (RT) for primary liver and gallbladder (GB) cancers, which are complex and require specialized multidisciplinary involvement. The role of RT continues to evolve for these cancers, and enthusiasm for routine use of RT has lagged behind other loco-regional therapies. Advances in technology, including motion management, image guidance, and treatment conformality, have improved the therapeutic ratio of RT and have achieved favorable clinical outcomes, demonstrating that RT should be a standard of care for liver and GB cancers. For example, RT was recently included for the first time as a reasonable option for liver cancer in the updated 2025 European Association for the Study of the Liver clinical practice guidelines.
Description
Keywords
Radiation therapy (RT) , Primary liver and gallbladder (GB) cancers
Citation
Barry, A. S., Ashman, J. B., Jethwa, K. R., Kim, H., Miller, E. D., Tao, R., Wojcieszynski, A. P. and Chuong, M. D. (2025) 'Back in the RACE: (Re)defining the role of radiation therapy in liver and gallbladder cancers', International Journal of Radiation Oncology* Biology* Physics, 123(1), pp.1-9. https://doi.org/10.1016/j.ijrobp.2025.04.041