• Bioaccessibility and bioavailability of a marine-derived multimineral, Aquamin-Magnesium 

  Felice, Valeria D.; O'Gorman, Denise M.; O'Brien, Nora M.; Hyland, Niall P. (MDPI AG, 2018)

  Introduction: Magnesium is an essential mineral involved in a range of key biochemical pathways. Several magnesium supplements are present on the market and their degree of bioavailability differs depending on the form of ...
• Respiratory control in the mdx mouse model of Duchenne muscular dystrophy 

  Burns, David P. (University College Cork, 2018)

  Duchenne muscular dystrophy (DMD) is a genetic disease that occurs in males due to the absence of the dystrophin (427 kDa) protein. Comprehensive studies on the control of breathing in DMD and animal models of the ...
• Recovery of respiratory function in mdx mice co-treated with neutralizing interleukin-6 receptor antibodies and Urocortin-2 

  Burns, David P.; Canavan, Leonie; Rowland, Jane; O'Flaherty, Robin; Brannock, Molly; Drummond, Sarah E.; O'Malley, Dervla; Edge, Deirdre; O'Halloran, Ken D. (John Wiley & Sons, Inc. on behalf of the Physiological Society, 2018-08-30)

  The mdx mouse model of Duchenne muscular dystrophy shows evidence of hypoventilation and pronounced diaphragm dysfunction. Six‐week‐old male mdx (n = 32) and wild‐type (WT; n = 32) mice received either saline (0.9% w/v) ...
• Functional classification of DNA variants by hybrid minigenes: identification of 30 spliceogenic variants of BRCA2 exons 17 and 18 

  Fraile-Bethencourt, Eugenia; Díez-Gómez, Beatriz; Velásquez-Zapata, Valeria; Acedo, Alberto; Sanz, David J.; Velasco, Eladio A. (Public Library of Science, 2017)

  Mutation screening of the breast cancer genes BRCA1 and BRCA2 identifies a large fraction of variants of uncertain clinical significance (VUS) whose functional and clinical interpretations pose a challenge for genomic ...
• The regulation of monoamine oxidase A gene expression by distinct variable number tandem repeats 

  Manca, Maurizio; Pessoa, Veridiana; Lopez, Ana Illera; Harrison, Patrick T.; Miyajima, Fabio; Sharp, Helen; Pickles, Andrew; Hill, Jonathan; Murgatroyd, Chris; Bubb, Vivien J.; Quinn, John P. (Humana Press, 2018)

  The monoamine oxidase A (MAOA) uVNTR (upstream variable number tandem repeat) is one of the most often cited examples of a gene by environment interaction (GxE) in relation to behavioral traits. However, MAOA possesses a ...

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