• Bile acids, bioactive signalling molecules in interoceptive gut-to-brain communication 

  Joyce, Susan A.; O'Malley, Dervla (John Wiley & Sons, Inc., 2022-04-12)

  Aside from facilitating solubilisation and absorption of dietary lipids and lipid-soluble vitamins, amphipathic bile acids (BAs) also act as bioactive signalling molecules. A plethora of conjugated or un-conjugated primary ...
• Emerging effects of tryptophan pathway metabolites and intestinal microbiota on metabolism and intestinal function 

  Hyland, Niall P.; Cavanaugh, Cassandre R.; Hornby, Pamela J. (Springer Wien, 2022-01-17)

  The metabolism of dietary tryptophan occurs locally in the gut primarily via host enzymes, with similar to 5% metabolized by gut microbes. Three major tryptophan metabolic pathways are serotonin (beyond the scope of this ...
• The gut microbiome influences the bioavailability of olanzapine in rats. 

  Cussotto, Sofia; Walsh, Jacinta; Golubeva, Anna V.; Zhdanov, Alexander V.; Strain, Conall R.; Fouhy, Fiona; Stanton, Catherine; Dinan, Timothy G.; Hyland, Niall P.; Clarke, Gerard; Cryan, John F.; Griffin, Brendan T. (Elsevier, 2021-04-02)

  Background: The role of the gut microbiome in the biotransformation of drugs has recently come under scrutiny. It remains unclear whether the gut microbiome directly influences the extent of drug absorbed after oral ...
• The art of facilitation: a delicate hormonal balance! 

  McDonald, Fiona B. (John Wiley & Sons Ltd., 2021-07-23)
• The role of renal afferent signalling in chronic intermittent hypoxia-induced sympathoexcitation and hypertension 

  AlMarabeh, Sara (University College Cork, 2021)

  Introduction: Sensory inputs from the kidney induce sympatho-excitation, and are integrated in brainstem regions receiving protective sensory inputs from high- and low-pressure baroreceptors. Blunted baroreflex control of ...

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