Stephenson, Kimberley Alix(University College Cork, 2022-01-07)
Duchenne Muscular Dystrophy (DMD) is a fatal musculoskeletal disorder that results in a loss of dystrophin in muscle fibres, leading to progressive immobility, chronic inflammation and premature death. Inflammation is ...
Keane, Jonathan M.; Walsh, Calum J.; Cronin, P.; Baker, Kevin J.; Melgar, Silvia; Cotter, Paul D.; Joyce, Susan A.; Gahan, Cormac G. M.; Houston, Aileen M.; Hyland, Niall P.(Springer Nature, 2022-11-23)
Background: Distinct sets of microbes contribute to colorectal cancer (CRC) initiation and progression. Some occur due to the evolving intestinal environment but may not contribute to disease. In contrast, others may play ...
Amaral, Margarida D.; Harrison, Patrick T.(Elsevier B.V., 2022-10-30)
Despite the major advances and successes in finding and establishing new treatments that tackle the basic defect in Cystic Fibrosis (CF), there is still an unmet need to bring these potentially curative therapies to all ...
Murphy, Ben T.; Mackrill, John J.; O'Halloran, Ken D.(John Wiley & Sons, Inc., 2022-10-17)
Cancer cachexia is defined as a multi-factorial syndrome characterised by an ongoing loss of skeletal muscle mass and progressive functional impairment, estimated to affect 50–80% of patients and responsible for 20% of ...
The current diagnosis of Congenital Heart Disease (CHD) in neonates relies on echocardiography. Its limited availability requires alternative screening procedures to prioritise newborns awaiting ultrasound. The routine ...
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