• Metabolomic pathway activity with genomic single-nucleotide polymorphisms associated with colorectal cancer recurrence and 5-year overall survival 

  Fleming, Christina A.; Mohan, Helen M.; O'Leary, Donal P.; Corrigan, M.; Redmond, H. Paul (Springer Nature Switzerland AG, 2022-03-03)

  Purpose: Metabolomic analysis in colorectal cancer (CRC) is an emerging research area with both prognostic and therapeutic targeting potential. We aimed to identify metabolomic pathway activity prognostic for CRC recurrence ...
• Gallstone ileus in an elderly orthopaedic patient managed with enterolithotomy: a video vignette 

  Ryan, Jessica M.; Flanagan, Michael; Connelly, Tara M.; Cooke, Fiachra; McCullough, Peter; Neary, Peter (John Wiley & Sons, Inc., 2021-08-25)
• Evaluation of the cytotoxic effects of the novel antineoplastic agent 1,4,5-Oxathiazinane-4,4-dioxide on triple negative breast cancer cells 

  Jinih, Marcel; Wang, Jiang Huai; Pfirrmann, Rolf W.; O'Leary, D. Peter; Corrigan, Mark A.; Redmond, Henry Paul (International Institute of Anticancer Research, 2021-05)

  Background/Aim: Adjuvant therapeutic options are limited for triple negative breast cancer (TNBC). Thus, we evaluated the cytotoxic effects of the newly synthesized antineoplastic agent 1,4,5-Oxathiazinane-4,4-dioxide (OTD) ...
• Piezoelectric inkjet coating of injection moulded, reservoir-tipped microneedle arrays for transdermal delivery 

  O'Mahony, Conor; Bocchino, Andrea; Haslinger, Michael J.; Brandstätter, Stefan; Außerhuber, Helene; Schossleitner, Klaudia; Clover, Anthony J. P.; Fechtig, Daniel (IOP Publishing, 2019-06-04)

  Coated microneedles have significant potential for use in transdermal delivery applications. In this paper, we describe the fabrication of microneedle master templates using microstereolithography techniques and subsequently ...
• Activation of both TLR and NOD signaling confers host innate immunity-mediated protection against microbial infection 

  Zhou, Huiting; Coveney, Andrew P.; Wu, Ming; Huang, Jie; Blankson, Siobhan; Zhao, He; O'Leary, D. Peter; Bai, Zhenjiang; Li, Yiping; Redmond, H. Paul; Wang, Jiang Huai; Wang, Jian (Frontiers Media, 2019-01-14)

  The detection of microbial pathogens relies on the recognition of highly conserved microbial structures by the membrane sensor Toll-like receptors (TLRs) and cytosolic sensor NOD-like receptors (NLRs). Upon detection, these ...

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