• Assessment of plasma B7-H3 levels in pediatric patients with different degrees of surgical stress 

  Li, Yan; Yuan, Qing; Huang, Jie; Li, Yi Ping; Pan, Jian; Feng, Xing; Zhang, Xue Guang; Wang, Jiang Huai; Wang, Jian (BioMed Central, 2016-07-26)

  Background: Surgical stress initiates a series of host hormone, metabolism and immune responses, which predominantly affect the homeostatic mechanism of patients with major surgery. B7-H3 is a co-stimulatory molecule and ...
• B7H3 ameliorates LPS-induced acute lung injury via attenuation of neutrophil migration and infiltration 

  Li, Yan; Huang, Jie; Foley, Niamh M.; Xu, Yunyun; Li, Yi Ping; Pan, Jian; Redmond, H. Paul; Wang, Jiang Huai; Wang, Jian (Nature Publishing Group, 2016-08)

  Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are characterized by an excessive inflammatory response within the lungs and severely impaired gas exchange resulting from alveolar-capillary barrier ...
• UBE2L6/UBCH8 and ISG15 attenuate autophagy in esophageal cancer cells 

  Falvey, Chloe M.; O'Donovan, Tracey R.; El-Mashad, Shereen M.; Nyhan, Michelle J.; O'Reilly, Seamus; McKenna, Sharon L. (Impact Journals, 2017-02-08)

  Esophageal cancer remains a poor prognosis cancer due to advanced stage of presentation and drug resistant disease. To understand the molecular mechanisms influencing response to chemotherapy, we examined genes that are ...
• B7-H3 augments inflammatory responses and exacerbates brain damage via amplifying NF-κB p65 and MAPK p38 activation during experimental pneumococcal meningitis 

  Chen, Xuqin; Li, Yan; Blankson, Siobhan; Liu, Min; Huang, Danping; Redmond, H. Paul; Huang, Jing; Wang, Jiang Huai; Wang, Jian (Public Library of Science, 2017-01-31)

  The costimulatory protein B7-H3 has been shown to play a contributory role in the development and progression of experimental pneumococcal meningitis by augmentation of the innate immunity-associated inflammatory response ...
• BRAFV600E mutation as a predictor of thyroid malignancy in indeterminate nodules: a systematic review and meta-analysis 

  Jinih, Marcel; Foley, Niamh M.; Osho, Olakunle; Houlihan, Lena; Toor, Asad Ali; Khan, Jehan Z.; Achackzai, Akbar A.; Redmond, H. Paul (Elsevier Ltd, 2016-11-22)

  Background: Thyroid nodules are usually diagnosed using fine-needle aspiration (FNA). The sensitivity limitations of FNA result in 10–30% of nodules being classified as “indeterminate”. The BRAFV600E mutation is associated ...

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