• Combination of electroporation delivered metabolic modulators with low-dose chemotherapy in osteosarcoma 

  Gill, Kheshwant S.; Fernandes, Philana; Bird, Brian; Soden, Declan M.; Forde, Patrick F. (Impact Journals, 2018)

  Background: Osteosarcoma accounts for roughly 60% of all malignant bone tumors in children and young adults. The five-year survival rate for localized tumors after surgery and chemotherapy is approximately 70% whilst it ...
• Impaction of swallowed dentures in the sigmoid colon requiring sigmoid colectomy 

  Flanagan, Michael; Clancy, Cillian; O'Riordain, Micheal G. (Elsevier Ltd, 2018)

  INTRODUCTION: Foreign body (FB) ingestion results in perforation in 1% of cases and is associated with significant morbidity and rarely mortality. Clinical presentation is variable and can present a diagnostic challenge. ...
• The utility of the radionuclide probe in parathyroidectomy for primary hyperparathyroidism 

  Lim, Ming Sheng; Jinih, Marcel; Ngai, C. H.; Foley, Niamh M.; Redmond, H. Paul (Royal College of Surgeons of England, 2017)

  INTRODUCTION: Parathyroidectomy is the definitive treatment for primary hyperparathyroidism but the intraoperative identification of adenomas is challenging. The aim of this study was to evaluate the utility of a radionuclide ...
• The impact of body composition parameters on ipilimumab toxicity and survival in patients with metastatic melanoma 

  Daly, Louise E.; Power, Derek G.; O'Reilly, Aine; Donnellan, Paul; Cushen, Samantha J.; O'Sullivan, Kathleen; Twomey, Maria; Woodlock, David P.; Redmond, H. Paul; Ryan, Aoife M. (Nature Publishing Group, 2017)

  Background: Body composition is an important predictor of drug toxicity and outcome. Ipilimumab (Ipi), a monoclonal antibody used to treat metastatic melanoma, has specific toxicities. No validated biomarkers that predict ...
• Polydopamine nanoparticles for treatment of acute inflammation-induced injury 

  Zhao, He; Zeng, Zhandong; Liu, Lin; Chen, Jiawen; Zhou, Huiting; Huang, Lili; Huang, Jie; Xu, Hua; Xu, Yunyun; Chen, Zhengrong; Wu, Yi; Guo, Wanliang; Wang, Jiang Huai; Wang, Jian; Liu, Zhuang (Royal Society of Chemistry, 2018-03-13)

  Nanotechnology-mediated anti-inflammatory therapy is emerging as a novel strategy for treatment of inflammation-induced injury. However, one of the main hurdles for these anti-inflammatory nano-drugs is their potential ...

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