SMARTProbe -: An informative biopsy needle with bioimpedance sensing for real-time breast lesion screening

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dc.contributor.author Ugwah, Justina A.
dc.contributor.author Bennett, Bill
dc.contributor.author O'Donnell, Brian
dc.contributor.author O'Sullivan, Martin
dc.contributor.author Moore, Eric
dc.date.accessioned 2021-08-17T09:21:29Z
dc.date.available 2021-08-17T09:21:29Z
dc.date.issued 2019-04
dc.identifier.citation Ugwah, J. A., Bennett, B., O'Donnell, B., O'Sullivan, M. and Moore, E. (2019) 'SMARTProbe -: An informative biopsy needle with bioimpedance sensing for real-time breast lesion screening', Smart Systems Integration; 13th International Conference and Exhibition on Integration Issues of Miniaturized Systems, Barcelona, Spain, 10-11 April, pp. 344-347. Available at: https://ieeexplore.ieee.org/abstract/document/8727824 (Accessed: 17 August 2021) en
dc.identifier.startpage 344 en
dc.identifier.endpage 347 en
dc.identifier.isbn 978-3-8007-4919-5
dc.identifier.uri http://hdl.handle.net/10468/11746
dc.description.abstract Patients who present with a breast lesion require clinical and radiological examination for breast disease detection. For a definitive diagnosis, biopsy under ultrasound guidance is performed for histological assessment to determine if lesion is malignant or benign. The biopsy needle, currently a passive instrument, if integrated with impedance sensing, can give real time information for use as a tissue discriminating tool. Bio-impedance is a technique which enables the use of three variables (resistance, reactance and phase angle) as indices of structural and functional biological variables. The frequency dependent electrical impulse gives the physiology and pathological information about the conductive and dielectric properties of cells. The differences in electrical properties of malignant and healthy tissues are associated with increased water and mineral content within tumor cells, the changes in membrane permeability, altered packing density as well as orientation of cells. The prototype SMARTProbe, with bioimpedance sensing, is able to discriminate healthy tissue from malignant and benign lesions in ex-vivo clinical investigation. The fabrication process of sensors allows for defined and constant electrode distance, which enables small alternate current to be used, thus, decreasing variability as a result of tissue heterogeneity. en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher VDE Verlag en
dc.relation.uri https://ieeexplore.ieee.org/abstract/document/8727824
dc.relation.uri https://www.vde-verlag.de/proceedings-de/564919053.html
dc.rights © 2019, VDE Verlag. All rights reserved. en
dc.subject Bio-impedance en
dc.subject Breast lesions en
dc.subject SMARTProbe en
dc.title SMARTProbe -: An informative biopsy needle with bioimpedance sensing for real-time breast lesion screening en
dc.type Conference item en
dc.internal.authorcontactother Eric Moore, Chemistry, University College Cork, Cork, Ireland. +353-21-490-3000 Email: eric.moore@tyndall.ie en
dc.internal.availability Full text available en
dc.date.updated 2021-08-17T08:50:57Z
dc.description.version Published Version en
dc.internal.rssid 578355373
dc.description.status Peer reviewed en
dc.internal.copyrightchecked Yes
dc.internal.licenseacceptance Yes en
dc.internal.conferencelocation Barcelona, Spain en
dc.internal.IRISemailaddress eric.moore@tyndall.ie en


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