• Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): a novel approach to investigate the wettability of pharmaceutical powder blends 

  Peddapatla, Raghhu V. G.; Ahmed, M. Rizwan; Blackshields, Caroline A.; Sousa-Gallagher, Maria J.; McSweeney, Sean; Kruse, Jacob; Crean, Abina M.; Fitzpatrick, Dara (American Chemical Society, 2017-09-19)

  The ability of Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS) to assess the wettability of powder blends is investigated. BARDS is a novel analytical technology developed based on the change in acoustic ...
• Synthesis of symmetrically and unsymmetrically substituted S,S-dialkyl phosphonodithioates 

  Jones, David J.; O'Leary, Eileen M.; O'Sullivan, Timothy P. (Elsevier, 2017-09-22)

  Herein, we report the synthesis of a range of S,S-dialkyl phosphonodithioates. Symmetrically substituted analogues were readily prepared from the corresponding phosphonic dichlorides in good to moderate yields, while ...
• Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): a rapid test for enteric coating thickness and integrity of controlled release pellet formulations 

  Dillon, Amy; Alfarsi, Anas; McSweeney, Seán; Krüse, Jacob; Griffin, Brendan; Devine, Ken; Sherry, Patricia; Henken, Stephan; Fitzpatrick, Stephen; Fitzpatrick, Dara (Elsevier B.V., 2018-04-12)

  There are no rapid dissolution based tests for determining coating thickness, integrity and drug concentration in controlled release pellets either during production or post-production. The manufacture of pellets requires ...
• The expanding horizon of alkyl quinolone signalling and communication in polycellular interactomes 

  Reen, F. Jerry; McGlacken, Gerard P.; O'Gara, Fergal (Oxford University Press on behalf of Federation of European Microbiological Societies, 2018-03-26)

  Population dynamics within natural ecosystems is underpinned by microbial diversity and the heterogeneity of host-microbe and microbe-microbe interactions. Small molecule signals that intersperse between species have been ...
• Substrate and catalyst effects in the enantioselective copper catalysed C–H insertion reactions of α-diazo-β-oxo sulfones 

  Maguire, Anita R.; Shiely, Amy; Clarke, Leslie Ann; Flynn, Chris; Buckley, Aoife; Ford, Alan; Lawrence, Simon E. (John Wiley & Sons, Inc., 2018-03-23)

  Excellent enantioselectivities of up to 98% ee are achieved employing the copper‐bis(oxazoline)‐NaBARF catalyst system in the C‐H insertion reactions of α‐diazo‐β‐oxo sulfones. The influence of variation of the bis(oxazoline) ...

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