• Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS): a rapid test for enteric coating thickness and integrity of controlled release pellet formulations 

  Dillon, Amy; Alfarsi, Anas; McSweeney, Seán; Krüse, Jacob; Griffin, Brendan; Devine, Ken; Sherry, Patricia; Henken, Stephan; Fitzpatrick, Stephen; Fitzpatrick, Dara (Elsevier B.V., 2018-04-12)

  There are no rapid dissolution based tests for determining coating thickness, integrity and drug concentration in controlled release pellets either during production or post-production. The manufacture of pellets requires ...
• The expanding horizon of alkyl quinolone signalling and communication in polycellular interactomes 

  Reen, F. Jerry; McGlacken, Gerard P.; O'Gara, Fergal (Oxford University Press on behalf of Federation of European Microbiological Societies, 2018-03-26)

  Population dynamics within natural ecosystems is underpinned by microbial diversity and the heterogeneity of host-microbe and microbe-microbe interactions. Small molecule signals that intersperse between species have been ...
• Substrate and catalyst effects in the enantioselective copper catalysed C–H insertion reactions of α-diazo-β-oxo sulfones 

  Maguire, Anita R.; Shiely, Amy; Clarke, Leslie Ann; Flynn, Chris; Buckley, Aoife; Ford, Alan; Lawrence, Simon E. (John Wiley & Sons, Inc., 2018-03-23)

  Excellent enantioselectivities of up to 98% ee are achieved employing the copper‐bis(oxazoline)‐NaBARF catalyst system in the C‐H insertion reactions of α‐diazo‐β‐oxo sulfones. The influence of variation of the bis(oxazoline) ...
• Predicting nucleation of isonicotinamide from the solvent - solute interactions of isonicotinamide in common organic solvents 

  Lynch, Mark B.; Lawrence, Simon E.; Nolan, Michael (American Chemical Society, 2018)

  The interactions of isonicotinamide (INA) with seven common solvents (acetic acid, acetonitrile, acetone, chloroform, ethyl acetate, and methanol) have been studied to examine solute – solvent effects on the nucleation of ...
• Cinchona-catalysed, enantioselective synthesis of β-Peroxycarboxylic acids, β-peroxyesters and β-peroxyalcohols 

  O'Reilly, Kate; Gupta, Manoj K.; Gandhi, Hiren K.; Kumar, Vydyula P.; Eccles, Kevin S.; Lawrence, Simon E.; O'Sullivan, Timothy P. (Bentham Science Publishers, 2016-09)

  A cinchona-catalysed, enantioselective oxa-Michael reaction of α,β-unsaturated aldehydes with either tert-butyl hydroperoxide or cumene hydroperoxide was developed. The reaction was optimised by screening of solvents, ...

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