• Localized partitioning of enantiomers in solid samples of sulfoxides: importance of sampling method in determination of enantiopurity 

  Flynn, Aaran J.; Ford, Alan; Maguire, Anita R. (American Chemical Society, 2020-07-02)

  Localized partitioning of amorphous enantioenriched aryl benzyl sulfoxides in the solid state can lead to substantial variation in enantiopurities, even for sulfoxides which do not show detectable levels of self-disproportionation ...
• Taming tosyl azide: the development of a scalable continuous diazo transfer process 

  Deadman, Benjamin J.; O'Mahony, Rosella M.; Lynch, Denis; Crowley, Daniel C.; Collins, Stuart G.; Maguire, Anita R. (Royal Society of Chemistry, 2016-03-01)

  Heat and shock sensitive tosyl azide was generated and used on demand in a telescoped diazo transfer process. Small quantities of tosyl azide were accessed in a 'one pot' batch procedure using shelf stable, readily available ...
• Design and synthesis of alpha-carboxy nucleoside phosphonate analogues and evaluation as HIV-1 reverse transcriptase-targeting agents 

  Keane, Sarah J.; Ford, Alan; Mullins, Nicholas D.; Maguire, Nuala M.; Legigan, Thibaut; Balzarini, Jan; Maguire, Anita R. (American Chemical Society, 2014-12-22)

  The synthesis of the first series of a new class of nucleoside phosphonate analogues is described. Addition of a carboxyl group at the α position of carbocyclic nucleoside phosphonate analogues leads to a novel class of ...
• Modern synthetic approaches to phosphorus-sulfur bond formation in organophosphorus compounds 

  Jones, David J.; O'Leary, Eileen M.; O'Sullivan, Timothy P. (John Wiley & Sons, Inc., 2020-06-12)

  Phosphorothioates, phosphonothioates, phosphinothioates and phosphonodithioates are organophosphorus compounds with widespread application, especially in the fields of agrochemicals, medicinal chemistry and materials ...
• Identification of N‐ or O‐alkylation of aromatic nitrogen heterocycles and N‐oxides using 1H–15N HMBC NMR spectroscopy 

  Sheehy, Kevin J.; Bateman, Lorraine M.; Flosbach, Niko T.; Breugst, Martin; Byrne, Peter A. (Wiley, 2020-06-09)

  A series of representative diazines and pyridine N‐oxides were subjected to alkylation using several different alkylating agents. The 15N NMR chemical shifts (δN values) of the diazines, pyridine N‐oxides and derived ...

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