Epidemiology of diabetes and complications among adults in the Republic of Ireland 1998-2015: a systematic review and meta-analysis

cb
Thumbnail Image
Files
1360.pdf(981.32 KB)
Published Version
Date
2016-02-09
Authors
Tracey, Marsha L.
Gilmartin, Michael
O'Neill, Kate N.
Fitzgerald, Anthony P.
McHugh, Sheena M.
Buckley, Claire M.
Canavan, Ronan J.
Kearney, Patricia M.
Journal Title
Journal ISSN
Volume Title
Publisher
BioMed Central
Published Version
10.1186/s12889-016-2818-2
Research Projects
Organizational Units
Journal Issue
Abstract
Background: Accurate estimates of the burden of diabetes are essential for future planning and evaluation of services. In Ireland, there is no diabetes register and prevalence estimates vary. The aim of this review was to systematically identify and review studies reporting the prevalence of diabetes and complications among adults in Ireland between 1998 and 2015 and to examine trends in prevalence over time. Methods: A systematic literature search was carried out using PubMed and Embase. Diabetes prevalence estimates were pooled by random-effects meta-analysis. Poisson regression was carried out using data from four nationally representative studies to calculate prevalence rates of doctor diagnosed diabetes between 1998 and 2015 and was also used to assess whether the rate of doctor diagnosed diabetes changed over time. Results: Fifteen studies (eight diabetes prevalence and seven complication prevalence) were eligible for inclusion. In adults aged 18 years and over, the national prevalence of doctor diagnosed diabetes significantly increased from 2.2 % in 1998 to 5.2 % in 2015 (p trend ≤ 0.001). The prevalence of diabetes complications ranged widely depending on study population and methodology used (6.5–25.2 % retinopathy; 3.2–32.0 % neuropathy; 2.5-5.2 % nephropathy). Conclusions: Between 1998 and 2015, there was a significant increase in the prevalence of doctor diagnosed diabetes among adults in Ireland. Trends in microvascular and macrovascular complications prevalence could not be examined due to heterogeneity between studies and the limited availability of data. Reliable baseline data are needed to monitor improvements in care over time at a national level. A comprehensive national diabetes register is urgently needed in Ireland.
Description
Keywords
Ireland , Prevalence , Trends , Diabetes , Microvascular , Macrovascular , Adults , Epidemiology
Citation
Tracey, M.L., Gilmartin, M., O’Neill, K., Fitzgerald, A.P., McHugh, S.M., Buckley, C.M., Canavan, R.J. and Kearney, P.M. (2016) 'Epidemiology of diabetes and complications among adults in the Republic of Ireland 1998-2015: a systematic review and meta-analysis', BMC Public Health, 16(1). doi: 10.1186/s12889-016-2818-2
Link to publisher’s version
URI
https://hdl.handle.net/10468/3145
Collections
Public Health - Journal Articles
Copyright
© 2016, Tracey et al. Open Access. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.