• Formulation and evaluation of anisamide-targeted amphiphilic cyclodextrin nanoparticles to promote therapeutic gene silencing in a 3D prostate cancer bone metastases model 

  Evans, James C.; Malhotra, Meenakshi; Fitzgerald, Kathleen A.; Guo, Jianfeng; Cronin, Michael F.; O'Brien, Fergal J.; Curtin, Caroline M.; Darcy, Raphael; O'Driscoll, Caitríona M. (ACS Publications, 2016-11-11)

  In recent years, RNA interference (RNAi) has emerged as a potential therapeutic offering the opportunity to treat a wide range of diseases, including prostate cancer. Modified cyclodextrins have emerged as effective gene ...
• Teaching prescribing: just what the doctor ordered? A thematic analysis of the views of newly qualified doctors 

  Hansen, Christina R.; Walsh, Elaine K.; Bradley, Colin P.; Sahm, Laura J. (MDPI, 2017-06-13)

  Undergraduate medical education has been criticised for failing to adequately prepare doctors for the task of prescribing. Pharmacists have been shown to improve medication use in hospitals. This study aims to elicit the ...
• Obesity takes its toll on visceral pain: High-fat diet induces toll-like receptor 4-dependent visceral hypersensitivity 

  Tramullas, Mónica; Finger, Beate C.; Dinan, Timothy G.; Cryan, John F. (PLoS, 2016-05-09)

  Exposure to high-fat diet induces both, peripheral and central alterations in TLR4 expression. Moreover, functional TLR4 is required for the development of high-fat diet-induced obesity. Recently, central alterations in ...
• Parental knowledge, attitudes and beliefs regarding fever in children: An interview study 

  Kelly, Maria; Sahm, Laura J.; Shiely, Frances; O'Sullivan, Ronan; McGillicuddy, Aoife; McCarthy, Suzanne (BioMed Central, 2016-07-11)

  Background: Fever is one of the most common childhood symptoms. It causes significant worry and concern for parents. Every year there are numerous cases of over- and under-dosing with antipyretics. Caregivers seek reassurance ...
• The application of molecular tethers in controlling axial chirality 

  Reen, Michael; O'Sullivan, Timothy P. (Bentham Science Publishers, 2016-06)

  Atropisomeric biaryl compounds are an attractive target in organic chemistry due to their abundance in nature and their utility as ligands in catalysis. Among the methods available for their synthesis, the use of chiral ...

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