• Randomised controlled trial of an intervention to improve parental knowledge and management practices of fever 

  Kelly, Maria; Sahm, Laura; McCarthy, Suzanne; O’Sullivan, Ronan; Mc Gillicuddy, Aoife; Shiely, Frances (BioMed Central, 2019-11-19)

  Background: We know that parents require resources which can assist them to improve fever knowledge and management practices. The purpose of this study, using an RCT, was to examine the effectiveness of an information ...
• Neurological and psychiatric adverse effects of long-term methylphenidate treatment in ADHD: A map of the current evidence 

  Krinzinger, Helga; Hall, Charlotte L.; Groom, Madeleine J.; Ansari, Mohammed T.; Banaschewski, Tobias; Buitelaar, Jan K.; Carucci, Sara; Coghill, David; Danckaerts, Marina; Dittmann, Ralf W.; Falissard, Bruno; Garas, Peter; Inglis K., Sarah K.; Kovshoff, Hanna; Kochhar, Puja; McCarthy, Suzanne; Nagy, Peter; Neubert, Antje; Roberts, Samantha; Sayal, Kapil; Sonuga-Barke, Edmund; Wong, Ian C. K.; Xia, Jun; Zuddas, Alessandro; Hollis, Chris; Konrad, Kerstin; Liddle, Elizabeth B. (Elsevier Ltd, 2019-09-20)

  Methylphenidate (MPH), the most common medication for children with Attention Deficit/Hyperactivity Disorder (ADHD) in many countries, is often prescribed for long periods of time. Any long-term psychotropic treatment in ...
• The virtually mature BNP (BNP1-32) is a precursor for the more effective BNP1-30 

  Schwiebs, Anja; Wang, Yong; Moore, Andrew M.; Zhu, Xudong; Pankow, Kristin; Siems, Wolf-Eberhard; Walther, Thomas (John Wiley & Sons, Inc., 2019-11-06)

  Background and Purpose: The B‐type natriuretic peptide (BNP1‐32) exerts vasorelaxing and cardioprotective activity. BNP is used as a biomarker for the diagnosis of cardiopathological conditions and recombinant BNP1‐32 as ...
• The cholesterol-lowering effect of oats and oat beta glucan: modes of action and potential role of bile acids and the microbiome 

  Joyce, Susan A.; Kamil, Alison; Fleige, Lisa; Gahan, Cormac G. M. (Frontiers Media, 2019-11-27)

  Consumption of sufficient quantities of oat products has been shown to reduce host cholesterol and thereby modulate cardiovascular disease risk. The effects are proposed to be mediated by the gel-forming properties of oat ...
• Microbial bile salt hydrolases mediate the efficacy of faecal microbiota transplant in the treatment of recurrent Clostridioides difficile infection 

  Mullish, Benjamin H.; McDonald, Julie A K.; Pechlivanis, Alexandros; Allegretti, Jessica R.; Kao, Dina; Barker, Grace F.; Kapila, Diya; Petrof, Elaine O.; Joyce, Susan A.; Gahan, Cormac G M.; Glegola-Madejska, Izabela; Williams, Horace R T.; Holmes, Elaine; Clarke, Thomas B.; Thursz, Mark R.; Marchesi, Julian R. (BMJ Publishing Group, 2019-02-11)

  Objective: Faecal microbiota transplant (FMT) effectively treats recurrent Clostridioides difficile infection (rCDI), but its mechanisms of action remain poorly defined. Certain bile acids affect C. difficile germination ...

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