• DNA vaccination for cervical cancer: Strategic optimisation of RALA mediated gene delivery from a biodegradable microneedle system 

  Cole, Grace; Ali, Ahlam A.; McCrudden, Cian M.; McBride, John W.; McCaffrey, Joanne; Robson, Tracey; Kett, Vicky L.; Dunne, Nicholas J.; Donnelly, Ryan F.; McCarthy, Helen O. (Elsevier, 2018-03-03)

  Dissolvable microneedles can be employed to deliver DNA to antigen presenting cells within the skin. However, this technology faces two main challenges: the poor transfection efficacy of pDNA following release from the ...
• The PHARMS (Patient Held Active Record of Medication Status) feasibility study: a research proposal 

  Walsh, Elaine; Sahm, Laura J.; Kearney, Patricia M.; Smithson, Henry; Kerins, David M.; Ngwa, Chrys; Fitzgerald, Ciara; McCarthy, Stephen; Connolly, Eimear; Dalton, Kieran; Byrne, Derina; Carey, Megan; Bradley, Colin (BioMed Central, 2018)

  Objective: Medication errors are a major source of preventable morbidity, mortality and cost and many occur at the times of hospital admission and discharge. Novel interventions (such as new methods of recording medication ...
• Wood ash residue causes a mixture of growth promotion and toxicity in Lemna minor 

  Jagodzinski, Lucas S.; O'Donoghue, Marian T.; Heffernan, Liam B.; van Pelt, Frank N. A. M.; O'Halloran, John; Jansen, Marcel A. K. (Elsevier, 2018-01-03)

  The use of wood as a sustainable biofuel results in the generation of residual wood ash. The ash contains high amounts of plant macronutrients such as phosphorus, potassium, calcium as well as several micronutrients. To ...
• Mild prenatal hypoxia-ischemia leads to social deficits and central and peripheral inflammation in exposed offspring 

  O'Driscoll, David J.; Felice, Valeria D.; Kenny, Louise C.; Boylan, Geraldine B.; O'Keeffe, Gerard W. (Elsevier B.V., 2018-01-20)

  Hypoxic-ischemic encephalopathy (HIE) resulting from intrauterine or perinatal hypoxic-ischemia (HI) is a leading cause of long-term neonatal neurodisability. While most studies of long-term outcome have focused on moderate ...
• Microbiota-related changes in bile acid and tryptophan metabolism are associated with gastrointestinal dysfunction in a mouse model of autism 

  Golubeva, Anna V.; Joyce, Susan A.; Moloney, Gerard M.; Burokas, Aurelijus; Sherwin, Eoin; Arboleya, Silvia; Flynn, Ian; Khochanskiy, Dmitry; Moya-Pérez, Angela; Peterson, Veronica; Rea, Kieran; Murphy, Kiera; Makarova, Olga; Buravkov, Sergey; Hyland, Niall P.; Stanton, Catherine; Clarke, Gerard; Gahan, Cormac G. M.; Dinan, Timothy G.; Cryan, John F. (Elsevier B.V., 2017-10-13)

  Autism spectrum disorder (ASD) is one of the most prevalent neurodevelopmental conditions worldwide. There is growing awareness that ASD is highly comorbid with gastrointestinal distress and altered intestinal microbiome, ...

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