• A study of magnesium stearate behaviour in pharmaceutical blends and tablets employing Broadband Acoustic Resonance Dissolution Spectroscopy (BARDS) 

  Peddapatla, Raghu V. G. (University College Cork, 2019)

  Magnesium Stearate (MgSt) is the most commonly used lubricant in pharmaceutical industries. Effects of MgSt on the final product have been extensively studied in batch processing. In recent times pharmaceutical companies ...
• The virtually mature BNP (BNP1-32) is a precursor for the more effective BNP1-30 

  Schwiebs, Anja; Wang, Yong; Moore, Andrew M.; Zhu, Xudong; Pankow, Kristin; Siems, Wolf-Eberhard; Walther, Thomas (John Wiley & Sons, Inc., 2019-11-06)

  Background and Purpose: The B‐type natriuretic peptide (BNP1‐32) exerts vasorelaxing and cardioprotective activity. BNP is used as a biomarker for the diagnosis of cardiopathological conditions and recombinant BNP1‐32 as ...
• Placental ageing in adverse pregnancy outcomes: Telomere shortening, cell senescence, and mitochondrial dysfunction 

  Manna, Samprikta; McCarthy, Cathal; McCarthy, Fergus P. (Hindawi, 2019-05-22)

  Preeclampsia is a multisystemic pregnancy disorder and a major cause of maternal and neonatal morbidity and mortality worldwide. The exact pathophysiology of preeclampsia remains unclear; however, it is speculated that the ...
• Age-dependent differences in pulmonary host responses in ARDS: A prospective observational cohort study 

  Schouten, Laura R.; van Kaam, Anton H.; Kohse, Franziska; Veltkamp, Floor; Bos, Lieuwe D.; de Beer, Friso M.; van Hooijdonk, Roosmarijn T.; Horn, Janneke; Straat, Marleen; Witteveen, Esther; Glas, Gerie J.; Wieske, Luuk; van Vught, Lonneke A.; Wiewel, Maryse A.; Ingelse, Sarah A.; Cortjens, Bart; van Woensel, Job B.; Bos, Albert P.; Walther, Thomas; Schultz, Marcus J.; Wösten-van Asperen, Roelie M. (Springer Open, 2019-05-14)

  Background: Results from preclinical studies suggest that age-dependent differences in host defense and the pulmonary renin–angiotensin system (RAS) are responsible for observed differences in epidemiology of acute respiratory ...
• Immunomodulatory therapeutic strategies in stroke 

  Malone, Kyle; Amu, Sylvie; Moore, Anne C.; Waeber, Christian (Frontiers Media, 2019-06-20)

  The role of immunity in all stages of stroke is increasingly being recognised, from the pathogenesis of risk factors to tissue repair, leading to the investigation of a range of immunomodulatory therapies. In the acute ...

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