Pharmacology and Therapeutics - Journal Articles

Pharmacology and Therapeutics - Journal Articles

 

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  • Seyerle, A. A.; Sitlani, C. M.; Noordam, R.; Gogarten, S. M.; Li, J.; Li, X.; Evans, D. S.; Sun, F.; Laaksonen, M. A.; Isaacs, A.; Kristiansson, K.; Highland, H. M.; Stewart, J. D.; Harris, T. B.; Trompet, S.; Bis, J. C.; Peloso, G. M.; Brody, J. A.; Broer, L.; Busch, E. L.; Duan, Q.; Stilp, A. M.; O'Donnell, C. J.; Macfarlane, P. W.; Floyd, J. S.; Kors, J. A.; Lin, H. J.; Li-Gao, R.; Sofer, T.; Mendez-Giraldez, R.; Cummings, S. R.; Heckbert, S. R.; Hofman, A.; Ford, I; Li, Y.; Launer, L. J.; Porthan, K.; Newton-Cheh, C.; Napier, M. D.; Kerr, K. F.; Reiner, A. P.; Rice, K. M.; Roach, J.; Buckley, Brendan M.; Soliman, E. Z.; de Mutsert, R.; Sotoodehnia, N.; Uitterlinden, A. G.; North, K. E.; Lee, C. R.; Gudnason, V; Sturmer, T.; Rosendaal, F. R.; Taylor, K. D.; Wiggins, K. L.; Wilson, J. G.; Chen, Y-D, I; Kaplan, R. C.; Wilhelmsen, K.; Cupples, L. A.; Salomaa, V; van Duijn, C.; Jukema, J. W.; Liu, Y.; Mook-Kanamori, D. O.; Lange, L. A.; Vasan, R. S.; Smith, A., V; Stricker, B. H.; Laurie, C. C.; Rotter, J., I; Whitsel, E. A.; Psaty, B. M.; Avery, C. L. (Nature Publishing Group, 2018)
    Thiazide diuretics, commonly used antihypertensives, may cause QT interval (QT) prolongation, a risk factor for highly fatal and difficult to predict ventricular arrhythmias. We examined whether common single-nucleotide ...
  • Malone, Kyle; Amu, Sylvie; Moore, Anne C.; Waeber, Christian (John Wiley & Sons, Inc., 2018-07-19)
    Stroke is a major cause of morbidity and mortality worldwide. Despite the intensive search for new therapies, hundreds of agents targeting various pathophysiological mechanisms have failed clinical trials, and the thrombolytic ...
  • Cambados, Nadia; Walther, Thomas; Nahmod, Karen; Tocci, Johanna M.; Rubinstein, Natalia; Boehme, Ilka; Simian, Marina; Sampayo, Rocio; Del Valle Suberbordes, Melisa; Kordon, Edith C.; Schere-Levy, Carolina (Impact Journals, 2017)
    Angiotensin (Ang) II, the main effector peptide of the renin-angiotensin system, has been implicated in multiple aspects of cancer progression such as proliferation, migration, invasion, angiogenesis and metastasis. ...
  • Tetzner, Anja; Naughton, Maura; Gebolys, Kinga; Eichhorst, Jenny; Sala, Esther; Villacañas, Óscar; Walther, Thomas (Elsevier B.V., 2018-05-21)
    The heptapeptide angiotensin (Ang)–(1–7) is part of the beneficial arm of the renin-angiotensin system. Ang-(1–7) has cardiovascular protective effects, stimulates regeneration, and opposes the often detrimental effects ...
  • Walsh, Jacinta; Griffin, Brendan T.; Clarke, Gerard; Hyland, Niall P. (John Wiley & Sons, Inc. on behalf of the British Pharmacological Society, 2018-05-21)
    The fate and activity of drugs are frequently dictated not only by the host per se but also by the microorganisms present in the gastrointestinal tract. The gut microbiome is known to, both directly and indirectly, affect ...

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