Pharmacology and Therapeutics - Journal Articles

Pharmacology and Therapeutics - Journal Articles

 

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  • Tetzner, Anja; Naughton, Maura; Gebolys, Kinga; Eichhorst, Jenny; Sala, Esther; Villacañas, Óscar; Walther, Thomas (Elsevier B.V., 2018-05-21)
    The heptapeptide angiotensin (Ang)–(1–7) is part of the beneficial arm of the renin-angiotensin system. Ang-(1–7) has cardiovascular protective effects, stimulates regeneration, and opposes the often detrimental effects ...
  • Walsh, Jacinta; Griffin, Brendan T.; Clarke, Gerard; Hyland, Niall P. (John Wiley & Sons, Inc. on behalf of the British Pharmacological Society, 2018-05-21)
    The fate and activity of drugs are frequently dictated not only by the host per se but also by the microorganisms present in the gastrointestinal tract. The gut microbiome is known to, both directly and indirectly, affect ...
  • Jones, David J.; O'Leary, Eileen M.; O'Sullivan, Timothy P. (Elsevier, 2017-09-22)
    Herein, we report the synthesis of a range of S,S-dialkyl phosphonodithioates. Symmetrically substituted analogues were readily prepared from the corresponding phosphonic dichlorides in good to moderate yields, while ...
  • Cole, Grace; Ali, Ahlam A.; McCrudden, Cian M.; McBride, John W.; McCaffrey, Joanne; Robson, Tracey; Kett, Vicky L.; Dunne, Nicholas J.; Donnelly, Ryan F.; McCarthy, Helen O. (Elsevier, 2018-03-03)
    Dissolvable microneedles can be employed to deliver DNA to antigen presenting cells within the skin. However, this technology faces two main challenges: the poor transfection efficacy of pDNA following release from the ...
  • Walsh, Elaine; Sahm, Laura J.; Kearney, Patricia M.; Smithson, W. Henry; Kerins, David M.; Ngwa, Chrys; Fitzgerald, Ciara; McCarthy, Stephen; Connolly, Eimear; Dalton, Kieran; Byrne, Derina; Carey, Megan; Bradley, Colin (BioMed Central, 2018)
    Objective: Medication errors are a major source of preventable morbidity, mortality and cost and many occur at the times of hospital admission and discharge. Novel interventions (such as new methods of recording medication ...

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