Continuous non-destructive monitoring of cell health using impedance based interdigitated electrode structured sensors

Paschero, Anna; McLoughlin, Eve; Moore, Eric J.

Continuous non-destructive monitoring of cell health using impedance based interdigitated electrode structured sensors

Files

AP_ContinuousAV2011.pdf(572.11 KB)

Accepted Version

Date

2011-06-10

Authors

Paschero, Anna

McLoughlin, Eve

Moore, Eric J.

Publisher

American Institute of Physics

Published Version

10.1063/1.3587464

Abstract

This article examines some preliminary tests which were performed in order to evaluate the best electrode configuration (width and spacing) for cell culture analyses. Biochips packaged with indium tin oxide (ITO) interdigitated electrodes (IDEs) were used to perform impedance measurements on A549 cells cultured on the surface of the biochip. Several tests were carried out using a 10 mM solution of Sodium Chloride (NaCl), cell medium and the cell culture itself to characterize some of the configurations already fabricated in the facilities at Tyndall National Institute.

Keywords

Biochemistry , Cellular biophysics , Optimisation , Electrochemical electrodes

Citation

PASCHERO, A., MCLOUGHLIN, E. & MOORE, E. J. CONTINUOUS NON-DESTRUCTIVE MONITORING OF CELL HEALTH USING IMPEDANCE BASED INTERDIGITATED ELECTRODE STRUCTURED SENSORS, 2011. In Tarasenko, O. ed., BIOLOGY, NANOTECHNOLOGY, TOXICOLOGY, AND APPLICATIONS: Proceedings of the 5th BioNanoTox and Applications International Research Conference, Little Rock, Arkansas, 4–5 November 2010. AIP, pp. 100-105.