Bacterial toxins: Offensive, defensive, or something else altogether?

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Bacterial toxins: Offensive, defensive, or something else altogether?

Rudkin, Justine K.; McLoughlin, Rachel M.; Preston, Andrew; Massey, Ruth C.
Date: 2017-09-21
Copyright: © 2017, Rudkin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Copyright information: https://creativecommons.org/licenses/by/4.0/
Related: http://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006452
Citation: Rudkin, J. K., McLoughlin, R. M., Preston, A. and Massey, R. C. (2017) 'Bacterial toxins: Offensive, defensive, or something else altogether?', PLOS Pathogens, 13(9), e1006452 (12pp). doi: 10.1371/journal.ppat.1006452
Published Version: 10.1371/journal.ppat.1006452

Abstract:

The secretion of proteins that damage host tissue is well established as integral to the infectious processes of many bacterial pathogens. However, recent advances in our understanding of the activity of toxins suggest that the attributes we have assigned to them from early in vitro experimentation have misled us into thinking of them as merely destructive tools. Here, we will discuss the multifarious ways in which toxins contribute to the lifestyle of bacteria and, by considering their activity from an evolutionary perspective, demonstrate how this extends far beyond their ability to destroy host tissue

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© 2017, Rudkin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Except where otherwise noted, this item's license is described as © 2017, Rudkin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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