Placental Growth Factor: A review of literature and future applications

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dc.contributor.author Hayes-Ryan, Deirdre
dc.contributor.author McCarthy, Fergus P.
dc.contributor.author O'Donoghue, Keelin
dc.contributor.author Kenny, Louise C.
dc.date.accessioned 2018-03-16T15:52:38Z
dc.date.available 2018-03-16T15:52:38Z
dc.date.issued 2018-03-10
dc.identifier.citation Hayes Ryan, D., McCarthy, F. P., O'Donoghue, K. and Kenny, L. C. 'Placental Growth Factor: A review of literature and future applications', Pregnancy Hypertension, In Press. doi: 10.1016/j.preghy.2018.03.003 en
dc.identifier.startpage 1 en
dc.identifier.endpage 16 en
dc.identifier.issn 2210-7789
dc.identifier.uri http://hdl.handle.net/10468/5631
dc.identifier.doi 10.1016/j.preghy.2018.03.003
dc.description.abstract Placental growth factor is an angiogenic protein, highly expressed during pregnancy, which correlates well with placental function. In this review, we highlight the origin, structure and function of Placental Growth Factor and its receptors. We discuss how their pro-angiogenic/anti-angiogenic synergism is critical for successful placentation and how their imbalance may be utilised as a diagnostic marker of disease or a potential therapeutic target for adverse pregnancy outcomes. en
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher Elsevier en
dc.relation.uri https://www.sciencedirect.com/science/article/pii/S2210778917304762
dc.rights © 2018 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license. en
dc.rights.uri http://creativecommons.org/licenses/by-nc-nd/4.0/ en
dc.subject Placental growth factor (PlGF) en
dc.subject PlGF concentrations en
dc.subject Pre-eclampsia en
dc.subject Adverse pregnancy outcomes en
dc.subject Pregnancy en
dc.title Placental Growth Factor: A review of literature and future applications en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Louise Kenny, Obstetrics & Gynaecology, University College Cork, Cork, Ireland. +353-21-490-3000 Email: l.kenny@ucc.ie en
dc.internal.availability Full text available en
dc.check.info Access to this article is restricted until 12 months after publication by request of the publisher. en
dc.check.date 2019-03-10
dc.date.updated 2018-03-16T15:46:51Z
dc.description.version Accepted Version en
dc.internal.rssid 430156273
dc.description.status Peer reviewed en
dc.identifier.journaltitle Pregnancy Hypertension en
dc.internal.copyrightchecked No !!CORA!! en
dc.internal.licenseacceptance Yes en
dc.internal.IRISemailaddress L.Kenny@ucc.ie en
dc.internal.IRISemailaddress fergus.mccarthy@ucc.ie en
dc.internal.IRISemailaddress k.odonoghue@ucc.ie en
dc.internal.IRISemailaddress deirdre.hayesryan@ucc.ie en


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© 2018 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license. Except where otherwise noted, this item's license is described as © 2018 International Society for the Study of Hypertension in Pregnancy. Published by Elsevier B.V. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license.
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