JavaScript is disabled for your browser. Some features of this site may not work without it.
The submission of new items to CORA is currently unavailable due to a repository upgrade. For further information, please contact cora@ucc.ie. Thank you for your understanding.
Citation:Cano, R., Mackey, K. and McGlacken, G. P. (2018) 'Recent advances in manganese-catalysed C–H activation: scope and mechanism', Catalysis Science & Technology, 8(5), pp. 1251-1266. doi: 10.1039/C7CY02514A
As a synthetic methodology, C–H activation represents a complimentary protocol to traditional cross-couplings such as the Suzuki–Miyaura and Stille reactions, by avoiding the extra synthetic steps required to install activating groups. C–H activation also often avoids the production of waste associated with B, Sn, halide etc. Pd-catalysed transformations have been most prominent in the C–H activation realm. However, as a society we are over-reliant on transitional metals, cost is increasing, and the accessible supply is dwindling. One potential solution is to develop chemistry using Earth Abundant Metals (EAMs). Manganese (Mn), in particular, demonstrates great promise. Since the publication of an excellent review by Ackermann in 2016 (ACS Catal. 2016, 6, 3743–3652), there has been a flurry of reports on Mn-catalysed C–H activation. We report here an overview of approximately 30 new papers, which include a number of notable advances since April 2016.
This website uses cookies. By using this website, you consent to the use of cookies in accordance with the UCC Privacy and Cookies Statement. For more information about cookies and how you can disable them, visit our Privacy and Cookies statement