• From youth to old age: therapeutic potential of microbiota interventions in the gut-brain-axis 

  Minuto, Chiara (University College Cork, 2022-08-17)

  There is a growing recognition of the involvement of the gut microbiota in the regulation of certain physiological and metabolic parameters across the life cycle of animals. A greater understanding of the microbiota changes ...
• Stress during puberty exerts sex-specific effects on depressive-like behavior and monoamine neurotransmitters in adolescence and adulthood 

  Harris, Erin P.; Villalobos-Manriquez, Francisca; Melo, Thieza G.; Clarke, Gerard; O'Leary, Olivia F. (Elsevier Inc., 2022-10-07)

  Psychiatric disorders including major depression are twice as prevalent in women compared to men. This sex difference in prevalence only emerges after the onset of puberty, suggesting that puberty may be a sensitive period ...
• The development and validation of a dashboard prototype for real-time suicide mortality data 

  Benson, Ruth; Brunsdon, C.; Rigby, J.; Corcoran, P.; Ryan, M.; Cassidy, E.; Dodd, P.; Hennebry, D.; Arensman, Ella (Frontiers Media S.A., 2022-08)

  Data visualisation is key to informing data-driven decision-making, yet this is an underexplored area of suicide surveillance. By way of enhancing a real-time suicide surveillance system model, an interactive dashboard ...
• Molecular, biochemical and behavioural evidence for a novel oxytocin receptor and serotonin 2C receptor heterocomplex 

  Chruścicka, Barbara; Cowan, Caitlin S. M.; Wallace Fitzsimons, Shauna E.; Borroto-Escuela, Dasiel O.; Druelle, Clémentine; Stamou, Panagiota; Bergmann, Cristian A.; Dinan, Timothy G.; Slattery, David A.; Fuxe, Kjell; Cryan, John F.; Schellekens, Harriët (Elsevier, 2021-02)

  The complexity of oxytocin-mediated functions is strongly associated with its modulatory effects on other neurotransmission systems, including the serotonin (5-hydroxytryptamine, 5-HT) system. Signalling between oxytocin ...
• Bifidobacterium longum counters the effects of obesity: partial successful translation from rodent to human 

  Schellekens, Harriët; Torres-Fuentes, Cristina; van de Wouw, Marcel; Long-Smith, Caitriona M.; Mitchell, Avery; Strain, Conall R.; Berding, Kirsten; Bastiaanssen, Thomaz F. S.; Rea, Kieran; Golubeva, Anna V.; Arboleya, Silvia; Verpaalen, Mathieu; Pusceddu, Matteo M.; Murphy, Amy; Fouhy, Fiona; Murphy, Kiera; Ross, R. Paul; Roy, Bernard L.; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F. (Elsevier B.V., 2021-01)

  The human gut microbiota has emerged as a key factor in the development of obesity. Certain probiotic strains have shown anti-obesity effects. The objective of this study was to investigate whether Bifidobacterium longum ...

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