• Annual Research Review: Critical windows – the microbiota–gut–brain axis in neurocognitive development 

  Cowan, Caitlin S. M.; Dinan, Timothy G.; Cryan, John F. (Wiley, 2019-11-26)

  The gut microbiota is a vast, complex, and fascinating ecosystem of microorganisms that resides in the human gastrointestinal tract. As an integral part of the microbiota–gut–brain axis, it is now being recognized that the ...
• The role of the microbiota in acute stress-induced myeloid immune cell trafficking 

  van de Wouw, Marcel; Lyte, Joshua M.; Boehme, Marcus; Sichetti, Marzia; Moloney, Gerard; Goodson, Michael S.; Kelley-Loughnane, Nancy; Dinan, Timothy G.; Clarke, Gerard; Cryan, John F. (Elsevier, 2019-12-05)

  There has been a growing recognition of the involvement of the gastrointestinal microbiota in the development of stress-related disorders. Acute stress leads to activation of neuroendocrine systems, which in turn orchestrate ...
• Gut-neuroimmune interactions: The unexpected role of the immune system in brain development 

  Spichak, Simon; Dinan, Timothy G.; Cryan, John F. (Portland Press, 2019-02-01)

  How does the immune system impact brain development?The exciting and somewhat unexpected relationship between the immune system and the brain has become one of the most fascinating topics in neuroscience. Even though the ...
• Gamma-aminobutyric acid-producing lactobacilli positively affect metabolism and depressive-like behaviour in a mouse model of metabolic syndrome 

  Patterson, Elaine; Ryan, Paul M.; Wiley, N.; Carafa, Ilaria; Sherwin, Eoin; Moloney, Gerard M.; Franciosi, E.; Mandal, R.; Wishart, D. S.; Tuohy, K.; Ross, R. Paul; Cryan, John F.; Dinan, Timothy G.; Stanton, Catherine (Springer Nature, 2019-11-08)

  Metabolic and neuroactive metabolite production represents one of the mechanisms through which the gut microbiota can impact health. One such metabolite, gamma-aminobutyric acid (GABA), can modulate glucose homeostasis and ...
• Focus on the essentials: tryptophan metabolism and the microbiome-gut-brain axis 

  Gheorghe, Cassandra Elise; Martin, Jason A.; Villalobos Manriquez, Francisca; Dinan, Timothy G.; Cryan, John F.; Clarke, Gerard (Elsevier Ltd., 2019-10-14)

  The gut-brain axis is a bidirectional communication system between the central nervous system and the gastrointestinal tract, in which serotonin (5-HT) functions as a key neurotransmitter. Recent research has increasingly ...

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