• The microbiota-gut-brain axis 

  Cryan, John F.; O'Riordan, Kenneth J.; Cowan, Caitlin S. M.; Sandhu, Kiran V.; Bastiaanssen, Thomaz F. S.; Boehme, Mcusra; Codagnone, Martin G.; Cussotto, Sofia; Fulling, Christine; Golubeva, Anna V.; Guzzetta, Katherine E.; Jaggar, Minal; Long-Smith, Caitriona M. .; Lyte, Joshua M.; Martin, Jason A.; Molinero-Perez, Alicia; Moloney, Gerard; Morelli, Emanuela; Morillas, Enrique; O'Connor, Rory; Cruz-Pereira, Joana S.; Peterson, Veronica L.; Rea, Kieran; Ritz, Nathaniel L.; Sherwin, Eoin; Spichak, Simon; Teichman, Emily M.; van de Wouw, Marcel; Ventura-Silva, Ana Paula; Wallace-Fitzsimons, Shauna E.; Hyland, Niall; Clarke, Gerard; Dinan, Timothy G. (American Physiological Society, 2019-08-28)

  The importance of the gut-brain axis in maintaining homeostasis has long been appreciated. However, the past 15 yr have seen the emergence of the microbiota (the trillions of microorganisms within and on our bodies) as one ...
• The role of the gut microbiome in the development of schizophrenia 

  Kelly, John R.; Minuto, Chiara; Cryan, John F.; Clarke, Gerard; Dinan, Timothy G. (Elsevier, 2020-04-23)

  Schizophrenia is a heterogeneous neurodevelopmental disorder involving the convergence of a complex and dynamic bidirectional interaction of genetic expression and the accumulation of prenatal and postnatal environmental ...
• The neurobiological effects of naturally-derived polyphenols and phospholipids in cellular & animal models of stress 

  Donoso, Francisco (University College Cork, 2019-12-20)

  The molecular and cellular basis of stress neurobiology remain an important research question in clinical science. Indeed, stress-related mental disorders, including depression and anxiety, are currently a major public ...
• Gut microbiome-mediated modulation of hepatic cytochrome P450 and P-glycoprotein: impact of butyrate and fructo-oligosaccharide-inulin 

  Walsh, Jacinta; Gheorghe, Cassandra E.; Lyte, Joshua M.; van de Wouw, Marcel; Boehme, Marcus; Dinan, Timothy G.; Cryan, John F.; Griffin, Brendan T.; Clarke, Gerard; Hyland, Niall P. (Wiley, 2020-04-26)

  Objectives: Our objective was to demonstrate microbial regulation of hepatic genes implicated in drug metabolism and transport using germ‐free (GF) mice and to explore the impact of a microbial metabolite, butyrate, and a ...
• Polyphenols selectively reverse early-life stress-induced behavioural, neurochemical and microbiota changes in the rat 

  Donoso, Francisco; Egerton, Sian; Bastiaanssen, Thomaz F. S.; Fitzgerald, Patrick; Gite, Snehal; Fouhy, Fiona; Ross, R. Paul; Stanton, Catherine; Dinan, Timothy G.; Cryan, John F. (Elsevier Ltd., 2020-04-10)

  There is a growing emphasis on the role of the microbiota-gut-brain axis as modulator of host behaviour and as therapeutic target for neuropsychiatric disorders. In addition, accumulating evidence suggests that early-life ...

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