Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases

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dc.contributor.author Bousquet, J. J.
dc.contributor.author Schünemann, H. J.
dc.contributor.author Togias, A.
dc.contributor.author Erhola, M.
dc.contributor.author Hellings, P. W.
dc.contributor.author Zuberbier, T.
dc.contributor.author Agache, I.
dc.contributor.author Ansotegui, I. J.
dc.contributor.author Anto, J. M.
dc.contributor.author Bachert, C.
dc.contributor.author Becker, S.
dc.contributor.author Bedolla-Barajas, M.
dc.contributor.author Bewick, M.
dc.contributor.author Bosnic-Anticevich, S.
dc.contributor.author Bosse, I.
dc.contributor.author Boulet, L. P.
dc.contributor.author Bourrez, J. M.
dc.contributor.author Brusselle, G.
dc.contributor.author Chavannes, N.
dc.contributor.author Costa, E.
dc.contributor.author Cruz, A. A.
dc.contributor.author Czarlewski, W.
dc.contributor.author Fokkens, W. J.
dc.contributor.author Fonseca, J. A.
dc.contributor.author Gaga, M.
dc.contributor.author Haahtela, T.
dc.contributor.author Illario, M.
dc.contributor.author Klimek, L.
dc.contributor.author Kuna, P.
dc.contributor.author Kvedariene, V.
dc.contributor.author Le, L. T. T.
dc.contributor.author Larenas-Linnemann, D.
dc.contributor.author Laune, D.
dc.contributor.author Lourenço, O. M.
dc.contributor.author Menditto, E.
dc.contributor.author Mullol, J.
dc.contributor.author Okamoto, Y.
dc.contributor.author Papadopoulos, N.
dc.contributor.author Pham-Thi, N.
dc.contributor.author Picard, R.
dc.contributor.author Pinnock, H.
dc.contributor.author Roche, N.
dc.contributor.author Roller-Wirnsberger, R. E.
dc.contributor.author Rolland, C.
dc.contributor.author Samolinski, B.
dc.contributor.author Sheikh, A.
dc.contributor.author Toppila-Salmi, S.
dc.contributor.author Tsiligianni, I.
dc.contributor.author Valiulis, A.
dc.contributor.author Valovirta, E.
dc.contributor.author Vasankari, T.
dc.contributor.author Ventura, M.-T.
dc.contributor.author Walker, S.
dc.contributor.author Williams, S.
dc.contributor.author Akdis, Cezmi A.
dc.contributor.author Annesi-Maesano, I.
dc.contributor.author Arnavielhe, S.
dc.contributor.author Basagana, X.
dc.contributor.author Bateman, Eric D.
dc.contributor.author Bedbrook, A.
dc.contributor.author Bennoor, K. S.
dc.contributor.author Benveniste, S.
dc.contributor.author Bergmann, K. C.
dc.contributor.author Bialek, S.
dc.contributor.author Billo, N.
dc.contributor.author Bindslev-Jensen, C.
dc.contributor.author Bjermer, L.
dc.contributor.author Blain, H.
dc.contributor.author Bonini, M.
dc.contributor.author Bonniaud, P.
dc.contributor.author Bouchard, J.
dc.contributor.author Briedis, V.
dc.contributor.author Brightling, C. E.
dc.contributor.author Brozek, J.
dc.contributor.author Buhl, R.
dc.contributor.author Buonaiuto, R.
dc.contributor.author Canonica, G. W.
dc.contributor.author Cardona, V.
dc.contributor.author Carriazo, A. M.
dc.contributor.author Carr, W.
dc.contributor.author Cartier, C.
dc.contributor.author Casale, T.
dc.contributor.author Cecchi, L.
dc.contributor.author Cepeda Sarabia, A. M.
dc.contributor.author Chkhartishvili, E.
dc.contributor.author Chu, D. K.
dc.contributor.author Cingi, C.
dc.contributor.author Colgan, E.
dc.contributor.author de Sousa, J. C.
dc.contributor.author Courbis, A. L.
dc.contributor.author Custovic, A.
dc.contributor.author Cvetkosvki, B.
dc.contributor.author D’Amato, G.
dc.contributor.author da Silva, J.
dc.contributor.author Dantas, C.
dc.contributor.author Dokic, D.
dc.contributor.author Dauvilliers, Y.
dc.contributor.author Dedeu, A.
dc.contributor.author De Feo, G.
dc.contributor.author Devillier, P.
dc.contributor.author Di Capua, S.
dc.contributor.author Dykewickz, M.
dc.contributor.author Dubakiene, R.
dc.contributor.author Ebisawa, M.
dc.contributor.author El-Gamal, Y.
dc.contributor.author Eller, E.
dc.contributor.author Emuzyte, R.
dc.contributor.author Farrell, J.
dc.contributor.author Fink-Wagner, A.
dc.contributor.author Fiocchi, A.
dc.contributor.author Fontaine, J. F.
dc.contributor.author Gemicioğlu, B.
dc.contributor.author Schmid-Grendelmeir, P.
dc.contributor.author Gamkrelidze, A.
dc.contributor.author Garcia-Aymerich, J.
dc.contributor.author Gomez, M.
dc.contributor.author González Diaz, S.
dc.contributor.author Gotua, M.
dc.contributor.author Guldemond, N. A.
dc.contributor.author Guzmán, M.-A.
dc.contributor.author Hajjam, J.
dc.contributor.author Hourihane, Jonathan O'B.
dc.contributor.author Humbert, M.
dc.contributor.author Iaccarino, G.
dc.contributor.author Ierodiakonou, D.
dc.contributor.author Illario, M.
dc.contributor.author Ivancevich, J. C.
dc.contributor.author Joos, G.
dc.contributor.author Jung, K.-S.
dc.contributor.author Jutel, M.
dc.contributor.author Kaidashev, I.
dc.contributor.author Kalayci, O.
dc.contributor.author Kardas, P.
dc.contributor.author Keil, T.
dc.contributor.author Khaitov, M.
dc.contributor.author Khaltaev, N.
dc.contributor.author Kleine-Tebbe, J.
dc.contributor.author Kowalski, M. L.
dc.contributor.author Kritikos, V.
dc.contributor.author Kull, I.
dc.contributor.author Leonardini, L.
dc.contributor.author Lieberman, P.
dc.contributor.author Lipworth, B.
dc.contributor.author Lodrup Carlsen, K. C.
dc.contributor.author Loureiro, C. C.
dc.contributor.author Louis, R.
dc.contributor.author Mair, A.
dc.contributor.author Marien, G.
dc.contributor.author Mahboub, B.
dc.contributor.author Malva, J.
dc.contributor.author Manning, P.
dc.contributor.author De Manuel Keenoy, E.
dc.contributor.author Marshall, G. D.
dc.contributor.author Masjedi, M. R.
dc.contributor.author Maspero, J. F.
dc.contributor.author Mathieu-Dupas, E.
dc.contributor.author Matricardi, P. M.
dc.contributor.author Melén, E.
dc.contributor.author Melo-Gomes, E.
dc.contributor.author Meltzer, E. O.
dc.contributor.author Menditto, E.
dc.contributor.author Mercier, J.
dc.contributor.author Miculinic, N.
dc.contributor.author Mihaltan, F.
dc.contributor.author Milenkovic, B.
dc.contributor.author Moda, G.
dc.contributor.author Mogica-Martinez, M.-D.
dc.contributor.author Mohammad, Y.
dc.contributor.author Montefort, S.
dc.contributor.author Monti, R.
dc.contributor.author Morais-Almeida, M.
dc.contributor.author Mösges, R.
dc.contributor.author Münter, L.
dc.contributor.author Muraro, A.
dc.contributor.author Murray, R.
dc.contributor.author Naclerio, R.
dc.contributor.author Napoli, L.
dc.contributor.author Namazova-Baranova, L.
dc.contributor.author Neffen, H.
dc.contributor.author Nekam, K.
dc.contributor.author Neou, A.
dc.contributor.author Novellino, E.
dc.contributor.author Nyembue, D.
dc.contributor.author O'Hehir, R.
dc.contributor.author Ohta, K.
dc.contributor.author Okubo, K.
dc.contributor.author Onorato, G.
dc.contributor.author Ouedraogo, S.
dc.contributor.author Pali-Schöll, I.
dc.contributor.author Palkonen, S.
dc.contributor.author Panzner, P.
dc.contributor.author Park, H.-S.
dc.contributor.author Pépin, J.-L.
dc.contributor.author Pereira, A.-M.
dc.contributor.author Pfaar, O.
dc.contributor.author Paulino, E.
dc.contributor.author Phillips, J.
dc.contributor.author Picard, R.
dc.contributor.author Plavec, D.
dc.contributor.author Popov, T. A.
dc.contributor.author Portejoie, F.
dc.contributor.author Price, D.
dc.contributor.author Prokopakis, E. P.
dc.contributor.author Pugin, B.
dc.contributor.author Raciborski, F.
dc.contributor.author Rajabian-Söderlund, R.
dc.contributor.author Reitsma, S.
dc.contributor.author Rodo, X.
dc.contributor.author Romano, A.
dc.contributor.author Rosario, N.
dc.contributor.author Rottem, M.
dc.contributor.author Ryan, D.
dc.contributor.author Salimäki, J.
dc.contributor.author Sanchez-Borges, M. M.
dc.contributor.author Sisul, J.-C.
dc.contributor.author Solé, D.
dc.contributor.author Somekh, D.
dc.contributor.author Sooronbaev, T.
dc.contributor.author Sova, M.
dc.contributor.author Spranger, O.
dc.contributor.author Stellato, C.
dc.contributor.author Stelmach, R.
dc.contributor.author Suppli Ulrik, C.
dc.contributor.author Thibaudon, M.
dc.contributor.author To, T.
dc.contributor.author Todo-Bom, A.
dc.contributor.author Tomazic, P. V.
dc.contributor.author Valero, A. A.
dc.contributor.author Valenta, R.
dc.contributor.author Valentin-Rostan, M.
dc.contributor.author van der Kleij, R.
dc.contributor.author Vandenplas, O.
dc.contributor.author Vezzani, G.
dc.contributor.author Viart, F.
dc.contributor.author Viegi, G.
dc.contributor.author Wallace, D.
dc.contributor.author Wagenmann, M.
dc.contributor.author Wang, D. Y.
dc.contributor.author Waserman, S.
dc.contributor.author Wickman, M.
dc.contributor.author Williams, D. M.
dc.contributor.author Wong, G.
dc.contributor.author Wroczynski, P.
dc.contributor.author Yiallouros, P. K.
dc.contributor.author Yorgancioglu, A.
dc.contributor.author Yusuf, O. M.
dc.contributor.author Zar, H. J.
dc.contributor.author Zeng, S.
dc.contributor.author Zernotti, M.
dc.contributor.author Zhang, L.
dc.contributor.author Zhong, N. S.
dc.contributor.author Zidarn, M.
dc.contributor.author Bousquet, J.
dc.contributor.author Hellings, P. W.
dc.contributor.author Aberer, W.
dc.contributor.author Agache, I.
dc.contributor.author Akdis, M.
dc.contributor.author Aliberti, M. R.
dc.contributor.author Almeida, R.
dc.contributor.author Amat, F.
dc.contributor.author Angles, R.
dc.contributor.author Annesi-Maesano, I.
dc.contributor.author Ansotegui, I. J.
dc.contributor.author Anto, J. M.
dc.contributor.author Arnavielle, S.
dc.contributor.author Asayag, E.
dc.contributor.author Asarnoj, A.
dc.contributor.author Arshad, H.
dc.contributor.author Avolio, F.
dc.contributor.author Bacci, E.
dc.contributor.author Bachert, C.
dc.contributor.author Baiardini, I.
dc.contributor.author Barbara, C.
dc.contributor.author Barbagallo, M.
dc.contributor.author Baroni, I.
dc.contributor.author Barreto, B. A.
dc.contributor.author Basagana, X.
dc.contributor.author Bateman, Eric D.
dc.contributor.author Bedolla-Barajas, M.
dc.contributor.author Bedbrook, A.
dc.contributor.author Bewick, M.
dc.contributor.author Beghé, B.
dc.contributor.author Bel, E. H.
dc.contributor.author Bergmann, K. C.
dc.contributor.author Bennoor, K. S.
dc.contributor.author Benson, M.
dc.contributor.author Bertorello, L.
dc.contributor.author Białoszewski, A. Z.
dc.contributor.author Bieber, T.
dc.contributor.author Bialek, S.
dc.contributor.author Bindslev-Jensen, C.
dc.contributor.author Bjermer, L.
dc.contributor.author Blain, H.
dc.contributor.author Blasi, F.
dc.contributor.author Blua, A.
dc.contributor.author Bochenska Marciniak, M.
dc.contributor.author Bogus-Buczynska, I.
dc.contributor.author ARIA Study Group, The
dc.contributor.author MASK Study Group, The
dc.date.accessioned 2019-10-29T15:53:39Z
dc.date.available 2019-10-29T15:53:39Z
dc.date.issued 2019
dc.identifier.citation Bousquet, J. J. ; Schünemann, H. J. ; Togias, A. ; Erhola, M. ; Hellings, P. W. ; Zuberbier, T. ; Agache, I. ; Ansotegui, I. J. ; Anto, J. M. ; Bachert, C. ; Becker, S. ; Bedolla-Barajas, M. ; Bewick, M. ; Bosnic-Anticevich, S. ; Bosse, I. ; Boulet, L. P. ; Bourrez, J. M. ; Brusselle, G. ; Chavannes, N. ; Costa, E. ; Cruz, A. A. ; Czarlewski, W. ; Fokkens, W. J. ; Fonseca, J. A. ; Gaga, M. ; Haahtela, T. ; Illario, M. ; Klimek, L. ; Kuna, P. ; Kvedariene, V. ; Le, L. T. T. ; Larenas-Linnemann, D. ; Laune, D. ; Lourenço, O. M. ; Menditto, E. ; Mullol, J. ; Okamoto, Y. ; Papadopoulos, N. ; Pham-Thi, N. ; Picard, R. ; Pinnock, H. ; Roche, N. ; Roller-Wirnsberger, R. E. ; Rolland, C. ; Samolinski, B. ; Sheikh, A. ; Toppila-Salmi, S. ; Tsiligianni, I. ; Valiulis, A. ; Valovirta, E. ; Vasankari, T. ; Ventura, M.-T. ; Walker, S. ; Williams, S. ; Akdis, C. A. ; Annesi-Maesano, I. ; Arnavielhe, S. ; Basagana, X. ; Bateman, E. ; Bedbrook, A. ; Bennoor, K. S. ; Benveniste, S. ; Bergmann, K. C. ; Bialek, S. ; Billo, N. ; Bindslev-Jensen, C. ; Bjermer, L. ; Blain, H. ; Bonini, M. ; Bonniaud, P. ; Bouchard, J. ; Briedis, V. ; Brightling, C. E. ; Brozek, J. ; Buhl, R. ; Buonaiuto, R. ; Canonica, G. W. ; Cardona, V. ; Carriazo, A. M. ; Carr, W. ; Cartier, C. ; Casale, T. ; Cecchi, L. ; Cepeda Sarabia, A. M. ; Chkhartishvili, E. ; Chu, D. K. ; Cingi, C. ; Colgan, E. ; de Sousa, J. C. ; Courbis, A. L. ; Custovic, A. ; Cvetkosvki, B. ; D’Amato, G. ; da Silva, J. ; Dantas, C. ; Dokic, D. ; Dauvilliers, Y. ; Dedeu, A. ; De Feo, G. ; Devillier, P. ; Di Capua, S. ; Dykewickz, M. ; Dubakiene, R. ; Ebisawa, M. ; El-Gamal, Y. ; Eller, E. ; Emuzyte, R. ; Farrell, J. ; Fink-Wagner, A. ; Fiocchi, A. ; Fontaine, J. F. ; Gemicioğlu, B. ; Schmid-Grendelmeir, P. ; Gamkrelidze, A. ; Garcia-Aymerich, J. ; Gomez, M. ; González Diaz, S. ; Gotua, M. ; Guldemond, N. A. ; Guzmán, M.-A. ; Hajjam, J. ; Hourihane, Jonathan O'B. ; Humbert, M. ; Iaccarino, G. ; Ierodiakonou, D. ; Illario, M. ; Ivancevich, J. C. ; Joos, G. ; Jung, K.-S. ; Jutel, M. ; Kaidashev, I. ; Kalayci, O. ; Kardas, P. ; Keil, T. ; Khaitov, M. ; Khaltaev, N. ; Kleine-Tebbe, J. ; Kowalski, M. L. ; Kritikos, V. ; Kull, I. ; Leonardini, L. ; Lieberman, P. ; Lipworth, B. ; Lodrup Carlsen, K. C. ; Loureiro, C. C. ; Louis, R. ; Mair, A. ; Marien, G. ; Mahboub, B. ; Malva, J. ; Manning, P. ; De Manuel Keenoy, E. ; Marshall, G. D. ; Masjedi, M. R. ; Maspero, J. F. ; Mathieu-Dupas, E. ; Matricardi, P. M. ; Melén, E. ; Melo-Gomes, E. ; Meltzer, E. O. ; Menditto, E. ; Mercier, J. ; Miculinic, N. ; Mihaltan, F. ; Milenkovic, B. ; Moda, G. ; Mogica-Martinez, M.-D. ; Mohammad, Y. ; Montefort, S. ; Monti, R. ; Morais-Almeida, M. ; Mösges, R. ; Münter, L. ; Muraro, A. ; Murray, R. ; Naclerio, R. ; Napoli, L. ; Namazova-Baranova, L. ; Neffen, H. ; Nekam, K. ; Neou, A. ; Novellino, E. ; Nyembue, D. ; O'Hehir, R. ; Ohta, K. ; Okubo, K. ; Onorato, G. ; Ouedraogo, S. ; Pali-Schöll, I. ; Palkonen, S. ; Panzner, P. ; Park, H.-S. ; Pépin, J.-L. ; Pereira, A.-M. ; Pfaar, O. ; Paulino, E. ; Phillips, J. ; Picard, R. ; Plavec, D. ; Popov, T. A. ; Portejoie, F. ; Price, D. ; Prokopakis, E. P. ; Pugin, B. ; Raciborski, F. ; Rajabian-Söderlund, R. ; Reitsma, S. ; Rodo, X. ; Romano, A. ; Rosario, N. ; Rottem, M. ; Ryan, D. ; Salimäki, J. ; Sanchez-Borges, M. M. ; Sisul, J.-C. ; Solé, D. ; Somekh, D. ; Sooronbaev, T. ; Sova, M. ; Spranger, O. ; Stellato, C. ; Stelmach, R. ; Suppli Ulrik, C. ; Thibaudon, M. ; To, T. ; Todo-Bom, A. ; Tomazic, P. V. ; Valero, A. A. ; Valenta, R. ; Valentin-Rostan, M. ; van der Kleij, R. ; V;enplas, O. ; Vezzani, G. ; Viart, F. ; Viegi, G. ; Wallace, D. ; Wagenmann, M. ; Wang, D. Y. ; Waserman, S. ; Wickman, M. ; Williams, D. M. ; Wong, G. ; Wroczynski, P. ; Yiallouros, P. K. ; Yorgancioglu, A. ; Yusuf, O. M. ; Zar, H. J. ; Zeng, S. ; Zernotti, M. ; Zhang, L. ; Zhong, N. S. ; Zidarn, M. ; Bousquet, J. ; Hellings, P. W. ; Aberer, W. ; Agache, I. ; Akdis, C. A. ; Akdis, M. ; Aliberti, M. R. ; Almeida, R. ; Amat, F. ; Angles, R. ; Annesi-Maesano, I. ; Ansotegui, I. J. ; Anto, J. M. ; Arnavielle, S. ; Asayag, E. ; Asarnoj, A. ; Arshad, H. ; Avolio, F. ; Bacci, E. ; Bachert, C. ; Baiardini, I. ; Barbara, C. ; Barbagallo, M. ; Baroni, I. ; Barreto, B. A. ; Basagana, X. ; Bateman, E. D. ; Bedolla-Barajas, M. ; Bedbrook, A. ; Bewick, M. ; Beghé, B. ; Bel, E. H. ; Bergmann, K. C. ; Bennoor, K. S. ; Benson, M. ; Bertorello, L. ; Białoszewski, A. Z. ; Bieber, T. ; Bialek, S. ; Bindslev-Jensen, C. ; Bjermer, L. ; Blain, H. ; Blasi, F. ; Blua, A. ; Bochenska Marciniak, M. ; Bogus-Buczynska, I. ; ARIA Study Group, The and MASK Study Group, The. (2019) 'Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases', Clinical and Translational Allergy, 9, 44 (15 pp.). DOI:10.1186/s13601-019-0279-2 en
dc.identifier.startpage 1
dc.identifier.endpage 15
dc.identifier.uri http://hdl.handle.net/10468/8911
dc.identifier.doi 10.1186/s13601-019-0279-2
dc.description.abstract Background: In all societies, the burden and cost of allergic and chronic respiratory diseases are increasing rapidly. Most economies are struggling to deliver modern health care effectively. There is a need to support the transformation of the health care system into integrated care with organizational health literacy. Main body: As an example for chronic disease care, MASK (Mobile Airways Sentinel NetworK), a new project of the ARIA (Allergic Rhinitis and its Impact on Asthma) initiative, and POLLAR (Impact of Air POLLution on Asthma and Rhinitis, EIT Health), in collaboration with professional and patient organizations in the field of allergy and airway diseases, are proposing real-life ICPs centred around the patient with rhinitis, and using mHealth to monitor environmental exposure. Three aspects of care pathways are being developed: (i) Patient participation, health literacy and self-care through technology-assisted “patient activation”, (ii) Implementation of care pathways by pharmacists and (iii) Next-generation guidelines assessing the recommendations of GRADE guidelines in rhinitis and asthma using real-world evidence (RWE) obtained through mobile technology. The EU and global political agendas are of great importance in supporting the digital transformation of health and care, and MASK has been recognized by DG Santé as a Good Practice in the field of digitally-enabled, integrated, person-centred care. Conclusion: In 20 years, ARIA has considerably evolved from the first multimorbidity guideline in respiratory diseases to the digital transformation of health and care with a strong political involvement. en
dc.description.sponsorship EIT Health (POLLAR); EUFOREA (ARIA)
dc.format.mimetype application/pdf en
dc.language.iso en en
dc.publisher BMC (part of Springer Nature) en
dc.relation.uri https://ctajournal.biomedcentral.com/articles/10.1186/s13601-019-0279-2
dc.rights © The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. en
dc.rights.uri https://creativecommons.org/licenses/by/4.0/
dc.subject Health care transformation en
dc.subject Care pathways en
dc.subject Rhinitis en
dc.subject ARIA en
dc.subject MASK en
dc.subject POLLAR en
dc.title Next-generation ARIA care pathways for rhinitis and asthma: a model for multimorbid chronic diseases en
dc.type Article (peer-reviewed) en
dc.internal.authorcontactother Jonathan Hourihane, Paediatrics & Child Health, University College Cork, Cork, Ireland. +353-21-490-3000 Email: j.hourihane@ucc.ie en
dc.internal.availability Full text available en
dc.description.version Published Version en
dc.contributor.funder EIT Health
dc.contributor.funder European Forum for Research and Education in Allergy and Airway Diseases
dc.description.status Peer reviewed en
dc.identifier.journaltitle Clinical and Translational Allergy en
dc.internal.IRISemailaddress j.hourihane@ucc.ie en
dc.identifier.articleid 44
dc.identifier.eissn 2045-7022


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© The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. Except where otherwise noted, this item's license is described as © The Author(s) 2019. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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