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Correlation between work impairment, scores of rhinitis severity and asthma using the MASK‐air® App
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Date
2020-01-29
Authors
Bédard, Annabelle
Antó, Josep M.
Fonseca, Joao A.
Arnavielhe, Sylvie
Bachert, Claus
Bedbrook, Anna
Bindslev-Jensen, Carsten
Bosnic-Anticevich, Sinthia
Cardona, Victoria
Cruz, Alvaro A.
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Publisher
John Wiley & Sons, Inc.
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Abstract
Background: In allergic rhinitis, a relevant outcome providing information on the effectiveness of interventions is needed. In MASK-air (Mobile Airways Sentinel Network), a visual analogue scale (VAS) for work is used as a relevant outcome. This study aimed to assess the performance of the work VAS work by comparing VAS work with other VAS measurements and symptom-medication scores obtained concurrently. Methods: All consecutive MASK-air users in 23 countries from June 1, 2016 to October 31, 2018 were included (14,189 users; 205,904 days). Geolocalized users self-assessed daily symptom control using the touchscreen functionality on their smart phone to click on VAS scores (ranging from 0 to 100) for overall symptoms (global), nose, eyes, asthma and work. Two symptom-medication scores were used: the modified EAACI CSMS score, and the MASK control score for rhinitis. To assess data quality, the intra-individual response variability (IRV) index was calculated. Results: A strong correlation was observed between VAS work and other VAS. The highest levels for correlation with VAS work and variance explained in VAS work were found with VAS global, followed by VAS nose, eye and asthma. In comparison to VAS global, the mCSMS and MASK control score showed a lower correlation with VAS work. Results are unlikely to be explained by a low quality of data arising from repeated VAS measures. Conclusions VAS work correlates with other outcomes (VAS global, nose, eye and asthma) but less well with a symptom-medication score. VAS work should be considered as a potentially useful AR outcome in intervention studies.
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Keywords
Asthma , MASK , Rhinitis , Score , Visual analogue scale
Citation
Bédard, A., Antó, J. M., Fonseca, J. A., Arnavielhe, S., Bachert, C., Bedbrook, A., Bindslev‐Jensen, C., Bosnic‐Anticevich, S., Cardona, V., Cruz, A. A., Fokkens, W. J., Garcia‐Aymerich, J., Hellings, P. W., Ivancevich, J. C., Klimek, L., Kuna, P., Kvedariene, V., Larenas‐Linnemann, D., Melén, E., Monti, R., Mösges, R., Mullol, J., Papadopoulos, N. G., Pham‐Thi, N., Samolinski, B., Tomazic, P. V ., Toppila‐Salmi, S., Ventura, M. T., Yorgancioglu, A., Bousquet, J., Pfaar, O., Basagaña, X. and The MASK study group (2020) ‘Correlation between work impairment, scores of rhinitis severity and asthma using the MASK‐air® App’, Allergy. doi: 10.1111/all.14204
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© 2020, John Wiley & Sons, Inc. This is the peer reviewed version of the following article: Lynch, T., Ryan, C., Hughes, C. M., Presseau, J., van Allen, Z. M., Bradley, C. P. and Cadogan, C. A. (2020) Bédard, A., Antó, J. M., Fonseca, J. A., Arnavielhe, S., Bachert, C., Bedbrook, A., Bindslev‐Jensen, C., Bosnic‐Anticevich, S., Cardona, V., Cruz, A. A., Fokkens, W. J., Garcia‐Aymerich, J., Hellings, P. W., Ivancevich, J. C., Klimek, L., Kuna, P., Kvedariene, V., Larenas‐Linnemann, D., Melén, E., Monti, R., Mösges, R., Mullol, J., Papadopoulos, N. G., Pham‐Thi, N., Samolinski, B., V Tomazic, P., Toppila‐Salmi, S., Ventura, M. T., Yorgancioglu, A., Bousquet, J., Pfaar, O., Basagaña, X. and The MASK study group (2020) ‘Correlation between work impairment, scores of rhinitis severity and asthma using the MASK‐air® App’, Allergy, doi: 10.1111/all.14204, which has been published in final form at https://doi.org/10.1111/all.14204. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.