Quality of life associated with maternal anxiety disorder in Russian children and adolescents with food allergy

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Dunn Galvin, Audrey
Treneva, Marina
Pampura, Alexander
Grebenko, Andrey
Makatsori, Melina
Munblit, Daniel
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Background: Food allergy negatively impacts the quality of life (QoL) and has been associated with increased maternal anxiety. There is currently a lack of data assessing QoL of food‐allergic children and adolescents in Russia. We aimed to evaluate the performance of the Food Allergy Quality of Life Questionnaire (FAQLQ) measures in a Russian sample of children, adolescents, and mothers and to investigate association between child QoL and maternal general anxiety. Methods: FAQLQ and Food Allergy Independent Measures (FAIM) were translated to Russian to be completed by participants. Mothers also filled the General Anxiety Disorder (GAD‐7) questionnaire. Reliability, construct, and discriminant validity of the FAQLQs and association between FAQLQ scores and general anxiety were assessed. Results: A total of 142 participants completed FAQLQ and FAIM. In total, 126 mothers completed GAD‐7 questionnaire. All FAQLQs showed excellent internal consistency (α > 0.94). The means for the FAQLQ‐PF, FAQLQ‐CF, and FAQLQ‐TF varied according to the number of foods avoided, severity of symptoms, and FAIM and GAD scores (ηp2 0.40 P < .001). One in 5 mothers had GAD‐7 score indicative of moderate‐to‐severe anxiety. Association strength between GAD and FAQLQ increased with age. GAD score was associated with FAQLQ‐PF score, controlling for multiple confounders. Conclusion: The FAQLQ showed good reliability and validity in Russian. This study identified number of foods avoided and reported reaction severity being associated with greater QoL impairment in Russian children and adolescents affected by food allergy. The significant association found between general anxiety in parents and QoL in children and adolescents has practice, screening, and resource implications. Key Message: This study found that 1 in 5 mothers of Russian food‐allergic children in given cohort had generalised anxiety disorder (GAD‐7) questionnaire score indicative of moderate to severe anxiety. This is three times higher than in general population norms. A third of mothers were above the threshold score for panic and social anxiety disorders. Relationship strength between maternal general anxiety and FAQLQ increased with age. Associations between the GAD‐7 score and parental form of FAQLQ score. Our results will add to ongoing work in the development of food allergy normed age scores to allow for precise measurement, interpretation of scores, and comparison across countries and cultures.
Children , Food allergy , Maternal anxiety , Quality of life
Dunn Galvin, A., Treneva, M., Pampura, A., Grebenko, A., Makatsori, M. and Munblit, D. (2019) 'Quality of life associated with maternal anxiety disorder in Russian children and adolescents with food allergy', Pediatric Allergy and Immunology, 31, pp. 71-84. doi: 10.1111/pai.13130
© 2019 EAACI and John Wiley and Sons A/S. This is the peer reviewed version of the following article: DunnGalvin, A, Treneva, M, Pampura, A, Grebenko, A, Makatsori, M, Munblit, D. Quality of life associated with maternal anxiety disorder in Russian children and adolescents with food allergy. Pediatr Allergy Immunol. 2020; 31: 78– 84, which has been published in final form at https://doi.org/10.1111/pai.13130. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.