International comparison of glycaemic control in people with type 1 diabetes: an update and extension

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dc.check.date2022-12-10
dc.check.infoAccess to this article is restricted until 12 months after publication by request of the publisher.en
dc.contributor.authorPrigge, R.
dc.contributor.authorMcKnight, J. A.
dc.contributor.authorWild, S. H.
dc.contributor.authorHaynes, A.
dc.contributor.authorJones, T. W.
dc.contributor.authorDavis, E. A.
dc.contributor.authorRami-Merhar, B.
dc.contributor.authorFritsch, M.
dc.contributor.authorPrchla, Christine
dc.contributor.authorLavens, A.
dc.contributor.authorDoggen, K.
dc.contributor.authorChao, S.
dc.contributor.authorAronson, R.
dc.contributor.authorBrown, R.
dc.contributor.authorIbfelt, E. H.
dc.contributor.authorSvensson, J.
dc.contributor.authorYoung, R.
dc.contributor.authorWarner, J. T.
dc.contributor.authorRobinson, H.
dc.contributor.authorLaatikainen, T.
dc.contributor.authorRautiainen, P.
dc.contributor.authorDelemer, B.
dc.contributor.authorSouchon, P. F.
dc.contributor.authorDiallo, A. M.
dc.contributor.authorHoll, R.W.
dc.contributor.authorSchmid, S. M.
dc.contributor.authorRaile, K.
dc.contributor.authorTigas, S.
dc.contributor.authorBargiota, A.
dc.contributor.authorZografou, I.
dc.contributor.authorLuk, A. O. Y.
dc.contributor.authorChan, J. C. N.
dc.contributor.authorDinneen, S. F.
dc.contributor.authorBuckley, Claire M.
dc.contributor.authorKgosidialwa, O.
dc.contributor.authorCherubini, V.
dc.contributor.authorGesuita, R.
dc.contributor.authorStrele, I.
dc.contributor.authorPildava, S.
dc.contributor.authorVeeze, H.
dc.contributor.authorAanstoot, H.-J.
dc.contributor.authorMul, D.
dc.contributor.authorJefferies, C.
dc.contributor.authorCooper, J. G.
dc.contributor.authorFjeld Løvaas, K.
dc.contributor.authorBattelino, T.
dc.contributor.authorDovc, K.
dc.contributor.authorBratina, N.
dc.contributor.authorEeg-Olofsson, K.
dc.contributor.authorSvensson, A.-M.
dc.contributor.authorGudbjornsdottir, S.
dc.contributor.authorGloba, E.
dc.contributor.authorZelinska, N.
dc.date.accessioned2021-12-17T10:06:21Z
dc.date.available2021-12-17T10:06:21Z
dc.date.issued2021-12-10
dc.description.abstractAims: To update and extend a previous cross-sectional international comparison of glycaemic control in people with type 1 diabetes. Methods: Data were obtained for 520,392 children and adults with type 1 diabetes from 17 population and five clinic-based data sources in countries or regions between 2016 and 2020. Median HbA1c(IQR) and proportions of individuals with HbA1c<58mmol/mol (<7.5%), 58 – 74 mmol/mol (7.5 – 8.9%) and ≥ 75 mmol/mol (≥ 9.0%) were compared between populations for individuals aged <15, 15 – 24 and ≥ 25years. Logistic regression was used to estimate the odds ratio (OR) of HbA1c< 58 mmol/mol (< 7.5%) relative to ≥ 58 mmol/mol (≥ 7.5%), stratified and adjusted for sex, age, and data source. Where possible, changes in the proportion of individuals in each HbA1c category compared to previous estimates were calculated. Results: Median HbA1c varied from 55 to 79 mmol/mol (7.2 to 9.4%) across data sources and age groups so a pooled estimate was deemed inappropriate. OR (95% CI) for HbA1c< 58 mmol/mol (<7.5 %) were 0.91 (0.90 – 0.92) for women compared to men, 1.68 (1.65 – 1.71) for people aged < 15 years and 0.81 (0.79 – 0.82) aged15 – 24 years compared to those aged ≥ 25 years. Differences between populations persisted after adjusting for sex, age, and data source. In general, compared to our previous analysis, the proportion of people with an HbA1c<58 mmol/l (<7.5%) increased and proportions of people with HbA1c≥ 75 mmol/mol (≥ 9.0%) decreased. Conclusions: Glycaemic control of type 1 diabetes continues to vary substantially between age groups and data sources. While some improvement over time has been observed, glycaemic control remains sub-optimal for most people with Type 1 diabetes.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleide14766en
dc.identifier.citationPrigge, R., McKnight, J. A., Wild, S. H., Haynes, A., Jones, T. W., Davis, E. A., Rami-Merhar, B., Fritsch, M., Prchla, C., Lavens, A., Doggen, K., Chao, S., Aronson, R., Brown, R., Ibfelt, E. H., Svensson, J., Young, R., Warner, J. T., Robinson, H., Laatikainen, T., Rautiainen, P., Delemer, B., Souchon, P. F., Diallo, A. M. , Holl, R., Schmid, S., Raile, K., Tigas, S., Bargiota, A., Zografou, I., Luk, A. O. Y., Chan, J. C. N., Dinneen, S. F., Buckley, C. M., Kgosidialwa, O., Cherubini, V., Gesuita, R., Strele, I., Pildava, S., Veeze, H., Aanstoot, H.-J., Mul, D., Jefferies, C., Cooper, J. G., Fjeld Løvaas, K., Battelino, T., Dovc, K., Bratina, N., Eeg-Olofsson, K., Svensson, A.-M., Gudbjornsdottir, S., Globa, E. and Zelinska, N. (2021) ‘International comparison of glycaemic control in people with type 1 diabetes: an update and extension’, Diabetic Medicine, e14766. doi: 10.1111/dme.14766en
dc.identifier.doi10.1111/dme.14766en
dc.identifier.eissn1464-5491
dc.identifier.issn0742-3071
dc.identifier.journaltitleDiabetic Medicineen
dc.identifier.urihttps://hdl.handle.net/10468/12352
dc.language.isoenen
dc.publisherJohn Wiley & Sons, Inc.en
dc.rights© 2021, John Wiley & Sons Ltd. This is the peer reviewed version of the following item: Prigge, R., McKnight, J. A., Wild, S. H., Haynes, A., Jones, T. W., Davis, E. A., Rami-Merhar, B., Fritsch, M., Prchla, C., Lavens, A., Doggen, K., Chao, S., Aronson, R., Brown, R., Ibfelt, E. H., Svensson, J., Young, R., Warner, J. T., Robinson, H., Laatikainen, T., Rautiainen, P., Delemer, B., Souchon, P. F., Diallo, A. M. , Holl, R., Schmid, S., Raile, K., Tigas, S., Bargiota, A., Zografou, I., Luk, A. O. Y., Chan, J. C. N., Dinneen, S. F., Buckley, C. M., Kgosidialwa, O., Cherubini, V., Gesuita, R., Strele, I., Pildava, S., Veeze, H., Aanstoot, H.-J., Mul, D., Jefferies, C., Cooper, J. G., Fjeld Løvaas, K., Battelino, T., Dovc, K., Bratina, N., Eeg-Olofsson, K., Svensson, A.-M., Gudbjornsdottir, S., Globa, E. and Zelinska, N. (2021) ‘International comparison of glycaemic control in people with type 1 diabetes: an update and extension’, Diabetic Medicine, e14766. doi: 10.1111/dme.14766, which has been published in final form at: https://doi.org/10.1111/dme.14766 This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.en
dc.subjectType 1 diabetesen
dc.subjectGlycaemic controlen
dc.subjectHbA1cen
dc.subjectRegisters of people with diabetesen
dc.titleInternational comparison of glycaemic control in people with type 1 diabetes: an update and extensionen
dc.typeArticle (peer-reviewed)en
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