Diagnostic accuracy of ultrasound for localising peripherally inserted central catheter tips in infants in the neonatal intensive care unit: a systematic review and meta-analysis

dc.contributor.authorDoyle, S. C.
dc.contributor.authorBergin, N. M.
dc.contributor.authorYoung, R.
dc.contributor.authorEngland, A.
dc.contributor.authorMcEntee, Mark F.
dc.date.accessioned2023-07-13T13:06:23Z
dc.date.available2023-07-13T13:06:23Z
dc.date.issued2022
dc.description.abstractBackground: Chest radiography after peripherally inserted central catheter insertion in infants is the reference standard method for verifying catheter tip position. The utilisation of ultrasound (US) for catheter placement confirmation in the neonatal and paediatric population has been the focus of many recent studies. Objective: In this systematic review we investigated the diagnostic accuracy of US for peripherally inserted central catheter tip confirmation in infants in the neonatal intensive care unit (NICU) Materials and methods: We conducted a systematic literature search of multiple databases. The study selection yielded eight articles, all of which had acceptable quality and homogeneity for inclusion in the meta-analysis. Sensitivity and specificity values were reported together with their respective 95% confidence intervals (CI). Results: After synthesising the eligible studies, we found that US had a sensitivity of 95.2% (95% CI 91.9–97.4%) and specificity of 71.4% (95% CI 59.4–81.6%) for confirming catheter tip position. Conclusion: Analyses indicated that US is an excellent imaging test for localising catheter tip position in the NICU when compared to radiography. Ultrasonography is a sensitive, specific and timely imaging modality for confirming PICC tip position. In cases where US is unable to locate malpositioned PICC tips, a chest or combined chest–abdominal radiograph should be performed. en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationDoyle, S. C., Bergin, N. M., Young, R., England, A. and McEntee, M. F. (2022) 'Diagnostic accuracy of ultrasound for localising peripherally inserted central catheter tips in infants in the neonatal intensive care unit: a systematic review and meta-analysis', Pediatric Radiology, 52(12), pp.2421-2430. doi: 10.1007/s00247-022-05379-7en
dc.identifier.doi10.1007/s00247-022-05379-7
dc.identifier.endpage2430
dc.identifier.issn3010449
dc.identifier.issued12
dc.identifier.journaltitlePediatric Radiologyen
dc.identifier.startpage2421
dc.identifier.urihttps://hdl.handle.net/10468/14736
dc.identifier.volume52
dc.language.isoenen
dc.publisherInstitute for Ionicsen
dc.rights© 2022, the Authors. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectCatheterizationen
dc.subjectInfanten
dc.subjectIntensive care uniten
dc.subjectNeonateen
dc.subjectPeripherally inserted central catheteren
dc.subjectRadiographyen
dc.subjectUltrasounden
dc.titleDiagnostic accuracy of ultrasound for localising peripherally inserted central catheter tips in infants in the neonatal intensive care unit: a systematic review and meta-analysisen
dc.typeArticle (peer-reviewed)en
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