Measuring the impact of systemic sclerosis on oral health‐related quality of life in a UK population

dc.contributor.authorAbdouh, Ismail
dc.contributor.authorPorter, Stephen
dc.contributor.authorFedele, Stefano
dc.contributor.authorElgendy, Nadia
dc.contributor.authorAboalshamat, Khalid
dc.contributor.authorBabkair, Hamzah Ali
dc.contributor.authorNí Riordain, Richeal
dc.contributor.funderTaibah Universityen
dc.contributor.funderUCLH Biomedical Research Centreen
dc.date.accessioned2022-02-10T14:40:53Z
dc.date.available2022-02-10T14:40:53Z
dc.date.issued2021-03-24
dc.description.abstractBackground: The objective of the present study was to identify the impact of systemic sclerosis (SSc) upon oral health-related quality of life (OHRQoL) of affected individuals resident in the UK. Methods: A total of 100 patients and their partners or carers were invited to complete questionnaires regarding the impact of SSc on quality of life and psychological well-being using valid and reliable patient-reported outcome measures (OHIP-14, MHISS, OIDP, MDAS and HADS). A total of 50 patients with SSc and 18 partners or carers who acted as controls returned the completed questionnaires. Statistical analyses were performed for comparisons of different variables. Results: All the mean scores of OHIP-14 (SSc [16.5 ± 12.4] Vs controls [6.06 ± 7.6, p = 0.001]) and MHISS components were significantly higher in patients than those of control group (SSc [21.26 ± 12] Vs controls [4.8 ± 7.3, p < 0.0001]). Majority of OIDP mean scores were significantly worse in patients compared with controls [SSc (10 ± 8.7) Vs controls (1.72 ± 3.4, p < 0.0001)]. The mean of total MDAS [SSc (11.7 ± 5.3) Vs controls (9.5 ± 4.4)] and HADS scores were higher in patients compared to controls (SSc depression [4.8 ± 3.3] and anxiety [6 ± 4.6] Vs controls [3.7 ± 3.1] [4.7 ± 3.9]). Conclusions: Although the present study is limited by the low response rate and its cross-sectional design, present results highlighted that systemic sclerosis has a negative impact on OHRQoL of the affected individuals; hence, the evaluation of associated psychological impact including anxiety and depression symptoms is needed to better understand, monitor and evaluate the disease comorbidity in patients with SSc.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationAbdouh, I., Porter, S., Fedele, S., Elledge, N., Aboalshamat, K., Babkair, H. A. and Ní Riordain, R. (2021) 'Measuring the impact of systemic sclerosis on oral health‐related quality of life in a UK population', Journal of Oral Pathology & Medicine, 50 (8), pp. 812-819. doi: 10.1111/jop.13177en
dc.identifier.doi10.1111/jop.13177en
dc.identifier.eissn1600-0714
dc.identifier.endpage819en
dc.identifier.issn0904-2512
dc.identifier.issued8en
dc.identifier.journaltitleJournal of Oral Pathology & Medicineen
dc.identifier.startpage812en
dc.identifier.urihttps://hdl.handle.net/10468/12551
dc.identifier.volume50en
dc.language.isoenen
dc.publisherJohn Wiley & Sons, Inc.en
dc.rights© 2021, John Wiley & Sons, Inc. This is the peer reviewed version of the following article: Abdouh, I., Porter, S., Fedele, S., Elledge, N., Aboalshamat, K., Babkair, H. A. and Ní Riordain, R. (2021) 'Measuring the impact of systemic sclerosis on oral health‐related quality of life in a UK population', Journal of Oral Pathology & Medicine, 50 (8), pp. 812-819. doi: 10.1111/jop.13177, which has been published in final form at https://doi.org/10.1111/jop.13177. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versionsen
dc.subjectOral healthen
dc.subjectQuality of lifeen
dc.subjectSystemic sclerosisen
dc.titleMeasuring the impact of systemic sclerosis on oral health‐related quality of life in a UK populationen
dc.typeArticle (peer-reviewed)en
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