Longitudinal associations between triglycerides and metabolic syndrome components in a Beijing adult population, 2007-2012

Simple item page
dc.contributor.authorTao, Li-Xin
dc.contributor.authorYang, Kun
dc.contributor.authorLiu, Xiang-Tong
dc.contributor.authorCao, Kai
dc.contributor.authorZhu, Hui-Ping
dc.contributor.authorLuo, Yan-Xia
dc.contributor.authorGuo, Jin
dc.contributor.authorWu, Li-Juan
dc.contributor.authorLi, Xia
dc.contributor.authorGuo, Xiu-Hua
dc.contributor.funderNational Natural Science Foundation of Chinaen
dc.date.accessioned2019-11-27T10:54:45Z
dc.date.available2019-11-27T10:54:45Z
dc.date.issued2016-06-01
dc.description.abstractBackground: Longitudinal associations between triglycerides (TG) and other metabolic syndrome (MetS) components have rarely been reported. The purpose was to investigate the longitudinal association between TG and other MetS components with time. Methods: The longitudinal study was established in 2007 on individuals who attended health check-ups at Beijing Tongren Hospital and Beijing Xiaotangshan Hospital. Data used in this study was based on 7489 participants who had at least three health check-ups over a period of 5-year follow up. Joint model was used to explore longitudinal associations between TG and other MetS components after adjusted for age. Results: There were positive correlations between TG and other MetS components except for high density lipoprotein (HDL), and the correlations increased with time. A negative correlation was displayed between TG and HDL, and the correlation also increased with time. Among all five pairs of TG and other MetS components, the marginal correlation between TG and body mass index (BMI) was the largest for both men and women. The marginal correlation between TG and fasting plasma glucose was the smallest for men, while the marginal correlation between TG and diastolic blood pressure was the smallest for women. Conclusions: The longitudinal association between TG and other MetS components increased with time. Among five pairs of TG and other MetS components, the longitudinal correlation between TG and BMI was the largest. It is important to closely monitor subjects with high levels of TG and BMI in health check-up population especially for women, because these two components are closely associated with development of hypertension, diabetes, cardiovascular disease and other metabolic diseases.en
dc.description.sponsorshipNational Natural Science Foundation of China (Serial Number: 81530087, 81502886, 81373099); Young core personal project & Beijing outstanding talent training project (Serial Number: 2014000020124G150); National Science & Technology Pillar Program in the Twelfth Five-year Plan Period of China (Serial Number: 2014ZX10004005-001)en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationTao, L.-X., Yang, K., Liu, X.-T., Cao, K., Zhu, H.-P., Luo, Y.-X., Guo, J., Wu, L.-J., Li, X. and Guo, X.-H. (2016) 'Longitudinal Associations between Triglycerides and Metabolic Syndrome Components in a Beijing Adult Population, 2007-2012', International Journal of Medical Sciences, 13(6), pp. 445-450. doi: 10.7150/ijms.14256en
dc.identifier.doi10.7150/ijms.14256en
dc.identifier.endpage450en
dc.identifier.issn1449-1907
dc.identifier.issued6en
dc.identifier.journaltitleInternational Journal of Medical Sciencesen
dc.identifier.startpage445en
dc.identifier.urihttps://hdl.handle.net/10468/9264
dc.identifier.volume13en
dc.language.isoenen
dc.publisherIVYSPRINGen
dc.rights© 2016, Ivyspring International Publisher. Reproduction is permitted for personal, noncommercial use, provided that the article is in whole, unmodified, and properly cited. See http://ivyspring.com/terms for terms and conditions.en
dc.subjectTriglyceridesen
dc.subjectMetabolic syndrome componentsen
dc.subjectLongitudinal correlationen
dc.subjectJoint modelen
dc.titleLongitudinal associations between triglycerides and metabolic syndrome components in a Beijing adult population, 2007-2012en
dc.typeArticle (peer-reviewed)en
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
v13p0445.pdf
Size:
459.18 KB
Format:
Adobe Portable Document Format
Description:
Published version
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Public Health - Journal Articles