Evidence of and recommendations for non-pharmacological interventions for common geriatric conditions: the SENATOR-ONTOP systematic review protocol.

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dc.contributor.authorAbraha, Iosief
dc.contributor.authorCruz-Jentoft, Alfonso
dc.contributor.authorSoiza, Roy L.
dc.contributor.authorO'Mahony, Denis
dc.contributor.authorCherubini, Antonio
dc.contributor.funderEuropean Commissionen
dc.contributor.funderSeventh Framework Programmeen
dc.date.accessioned2017-02-24T16:22:58Z
dc.date.available2017-02-24T16:22:58Z
dc.date.issued2015-01-01
dc.date.updated2017-02-24T16:14:15Z
dc.description.abstractIntroduction: Non-pharmacological therapies for common chronic medical conditions in older patients are underused in clinical practice. We propose a protocol for the assessment of the evidence of non-pharmacological interventions to prevent or treat relevant outcomes in several prevalent geriatric conditions in order to provide recommendations. Methods and analysis: The conditions of interest for which the evidence about efficacy of non-pharmacological interventions will be searched include delirium, falls, pressure sores, urinary incontinence, dementia, heart failure, orthostatic hypotension, sarcopaenia and stroke. For each condition, the following steps will be undertaken: (A) prioritising clinical questions; (B) retrieving the evidence (MEDLINE, the Cochrane Library, CINAHL and PsychINFO will be searched to identify systematic reviews); (C) assessing the methodological quality of the evidence (risk of bias according to the Cochrane method will be applied to the primary studies retrieved from the systematic reviews); (D) developing recommendations based on the evidence (Grading of Recommendations Assessment, Development and Evaluation (GRADE) items—risk of bias, imprecision, inconsistency, indirectness and publication bias—will be used to rate the overall evidence and develop recommendations). Dissemination: For each target condition, at least one systematic overview concerning the evidence of non-pharmacological interventions will be produced and published in peer-reviewed journals.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationAbraha, I., Cruz-Jentoft, A., Soiza, R. L., O'Mahony, D. and Cherubini, A. (2015) 'Evidence of and recommendations for non-pharmacological interventions for common geriatric conditions: the SENATOR-ONTOP systematic review protocol', BMJ Open, 5(1). doi:10.1136/bmjopen-2014-007488en
dc.identifier.doi10.1136/bmjopen-2014-007488
dc.identifier.endpagee007488-6en
dc.identifier.issn2044-6055
dc.identifier.journaltitleBmj Openen
dc.identifier.startpagee007488-1en
dc.identifier.urihttps://hdl.handle.net/10468/3692
dc.identifier.volume5en
dc.language.isoenen
dc.publisherBMJ Publishing Groupen
dc.relation.projectinfo:eu-repo/grantAgreement/EC/FP7::SP1::HEALTH/305930/EU/Development and clinical trials of a new Software ENgine for the Assessment & Optimization of drug and non-drug Therapy in Older peRsons/SENATORen
dc.rights© 2015, The Authors. Published by the BMJ Publishing Group Limited. This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.en
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectOlder peopleen
dc.subjectSENATOR-ONTOP systematic review protocolen
dc.subjectNon-pharmacological interventionsen
dc.subjectChronic medical conditionsen
dc.subjectOlder patientsen
dc.titleEvidence of and recommendations for non-pharmacological interventions for common geriatric conditions: the SENATOR-ONTOP systematic review protocol.en
dc.typeArticle (non peer-reviewed)en
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