Phenotyping for a personalised approach to CVD prevention

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dc.availability.bitstreamcontrolled
dc.contributor.advisorEustace, Joeen
dc.contributor.advisorFanning, Liam J.en
dc.contributor.authorMcEvoy, John William
dc.date.accessioned2022-09-23T14:06:15Z
dc.date.available2022-09-23T14:06:15Z
dc.date.issued2022-03-01
dc.date.submitted2022-03-01
dc.descriptionControlled Access
dc.description.abstractCardiovascular disease (CVD) prevention requires interventions at the level of the population (public health) and at the level of individuals (medical care). Therapeutic options to reduce the risk of CVD among at risk individuals are increasingly available, but access to and implementation of these evidence-based therapies is suboptimal and costs to health systems are often a deterrent to payers. Therefore, advanced phenotyping of individuals, for example using biomarkers of subclinical CVD, in order to better personalize their preventive care is an attractive approach. In the corpus of work presented for this PhD by prior publication, a series of eleven published papers is included that examines the role of biomarkers of subclinical CVD (specifically high-sensitivity Troponin measured in blood and coronary artery calcium imaging) in the management of persons with hypertension and abnormalities in diastolic blood pressure.en
dc.description.statusNot peer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationMcEvoy, J. W. 2022. Phenotyping for a personalised approach to CVD prevention. PhD Thesis, University College Cork.en
dc.identifier.endpage445en
dc.identifier.urihttps://hdl.handle.net/10468/13660
dc.language.isoenen
dc.publisherUniversity College Corken
dc.rights© 2022, John William McEvoy.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectCardiovascular diseaseen
dc.subjectHypertensionen
dc.subjectCardiac biomarkersen
dc.subjectPhenotypingen
dc.subjectPreventionen
dc.titlePhenotyping for a personalised approach to CVD preventionen
dc.typeDoctoral thesisen
dc.type.qualificationlevelDoctoralen
dc.type.qualificationnamePhD - Doctor of Philosophyen
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