STOPP/START criteria for potentially inappropriate prescribing in older people: version 2

dc.contributor.authorO'Mahony, Denis
dc.contributor.authorO'Sullivan, David.
dc.contributor.authorByrne, Stephen
dc.contributor.authorO'Connor, Marie N.
dc.contributor.authorRyan, Cristin
dc.contributor.authorGallagher, Paul F.
dc.contributor.funderHealth Research Boarden
dc.description.abstractPurpose: screening tool of older people’s prescriptions (STOPP) and screening tool to alert to right treatment (START) criteria were first published in 2008. Due to an expanding therapeutics evidence base, updating of the criteria was required. Methods: we reviewed the 2008 STOPP/START criteria to add new evidence-based criteria and remove any obsolete criteria. A thorough literature review was performed to reassess the evidence base of the 2008 criteria and the proposed new criteria. Nineteen experts from 13 European countries reviewed a new draft of STOPP & START criteria including proposed new criteria. These experts were also asked to propose additional criteria they considered important to include in the revised STOPP & START criteria and to highlight any criteria from the 2008 list they considered less important or lacking an evidence base. The revised list of criteria was then validated using the Delphi consensus methodology. Results: the expert panel agreed a final list of 114 criteria after two Delphi validation rounds, i.e. 80 STOPP criteria and 34 START criteria. This represents an overall 31% increase in STOPP/START criteria compared with version 1. Several new STOPP categories were created in version 2, namely antiplatelet/anticoagulant drugs, drugs affecting, or affected by, renal function and drugs that increase anticholinergic burden; new START categories include urogenital system drugs, analgesics and vaccines. Conclusion: STOPP/START version 2 criteria have been expanded and updated for the purpose of minimizing inappropriate prescribing in older people. These criteria are based on an up-to-date literature review and consensus validation among a European panel of experts.en
dc.description.sponsorshipHealth Research Board of Ireland (HRB grant number HRA_HSR/2010/14)en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.identifier.citationO'Mahony, D., O'Sullivan, D., Byrne, S., O'Connor, M. N., Ryan, C. and Gallagher, P. (2015) 'STOPP/START criteria for potentially inappropriate prescribing in older people: version 2', Age and Ageing, 44(2), pp. 213-218. doi:10.1093/ageing/afu145en
dc.identifier.journaltitleAge and Ageingen
dc.publisherOxford University Pressen
dc.rights© The Authors 2014. Published by Oxford University Press on behalf of the British Geriatrics Society. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (, which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.comen
dc.subjectInappropriate prescribingen
dc.subjectOlder peopleen
dc.subjectSTOPP/START criteriaen
dc.titleSTOPP/START criteria for potentially inappropriate prescribing in older people: version 2en
dc.typeArticle (peer-reviewed)en
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