Effectiveness of non-pharmacological interventions to prevent falls in older people: a systematic overview. The SENATOR Project ONTOP Series

dc.contributor.authorRimland, Joseph M.
dc.contributor.authorAbraha, Iosief
dc.contributor.authorDell’Aquila, Giuseppina
dc.contributor.authorCruz-Jentoft, Alfonso
dc.contributor.authorSoiza, Roy
dc.contributor.authorGudmundsson, Adalsteinn
dc.contributor.authorPetrovic, Mirko
dc.contributor.authorO'Mahony, Denis
dc.contributor.authorTodd, Chris
dc.contributor.authorCherubini, Antonio
dc.contributor.funderSeventh Framework Programmeen
dc.description.abstractBackground: Falls are common events in older people, which cause considerable morbidity and mortality. Non-pharmacological interventions are an important approach to prevent falls. There are a large number of systematic reviews of non-pharmacological interventions, whose evidence needs to be synthesized in order to facilitate evidence-based clinical decision making. Objectives: To systematically examine reviews and meta-analyses that evaluated non-pharmacological interventions to prevent falls in older adults in the community, care facilities and hospitals. Methods: We searched the electronic databases Pubmed, the Cochrane Database of Systematic Reviews, EMBASE, CINAHL, PsycINFO, PEDRO and TRIP from January 2009 to March 2015, for systematic reviews that included at least one comparative study, evaluating any non-pharmacological intervention, to prevent falls amongst older adults. The quality of the reviews was assessed using AMSTAR and ProFaNE taxonomy was used to organize the interventions. Results: Fifty-nine systematic reviews were identified which consisted of single, multiple and multi-factorial non-pharmacological interventions to prevent falls in older people. The most frequent ProFaNE defined interventions were exercises either alone or combined with other interventions, followed by environment/assistive technology interventions comprising environmental modifications, assistive and protective aids, staff education and vision assessment/correction. Knowledge was the third principle class of interventions as patient education. Exercise and multifactorial interventions were the most effective treatments to reduce falls in older adults, although not all types of exercise were equally effective in all subjects and in all settings. Effective exercise programs combined balance and strength training. Reviews with a higher AMSTAR score were more likely to contain more primary studies, to be updated and to perform meta-analysis. Conclusions: The aim of this overview of reviews of non-pharmacological interventions to prevent falls in older people in different settings, is to support clinicians and other healthcare workers with clinical decision-making by providing a comprehensive perspective of findings.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.identifier.citationRimland, J.M., Abraha, I., Dell’Aquila, G., Cruz-Jentoft, A., Soiza, R., Gudmundsson, A., Petrovic, M., O'Mahony, D., Todd, C. and Cherubini, A. (2016) ‘Effectiveness of non-pharmacological interventions to prevent falls in older people: a systematic overview. The SENATOR Project ONTOP Series’, PLoS ONE, 11(8), e0161579 (29pp). doi:10.1371/journal.pone.0161579en
dc.identifier.doi10.1371/journal. pone.0161579
dc.identifier.journaltitlePLoS ONEen
dc.publisherPublic Library of Scienceen
dc.relation.projectinfo:eu-repo/grantAgreement/EC/FP7::SP1::HEALTH/305930/EU/Development and clinical trials of a new Software ENgine for the Assessment & Optimization of drug and non-drug Therapy in Older peRsons/SENATORen
dc.relation.projectinfo:eu-repo/grantAgreement/NHMRC/NHMRC Project Grants/512326/AU/Exercise therapy for prevention of falls in people with Parkinsons disease: a randomised controlled trial./en
dc.rights© 2016, Rimland et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en
dc.subjectRandomized controlled trialsen
dc.subjectTerm care facilitiesen
dc.subjectWhole-body vibrationen
dc.subjectTai Chien
dc.subjectExercise interventionsen
dc.subjectCognitive impairmenten
dc.subjectReduce fallsen
dc.subjectPhysical exerciseen
dc.subjectCataract surgeryen
dc.titleEffectiveness of non-pharmacological interventions to prevent falls in older people: a systematic overview. The SENATOR Project ONTOP Seriesen
dc.typeArticle (peer-reviewed)en
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