Probiotic peanut oral immunotherapy is associated with long-term persistence of 8-week sustained unresponsiveness and long-lasting quality-of-life improvement

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Date
2022-04-29
Authors
Loke, Paxton
Hsiao, Kuang-Chih
Chebar Lozinsky, Adriana
Ashley, Sarah E.
Lloyd, Melanie
Pitkin, Sigrid
Axelrad, Christine Jean
Jayawardana, Kaushala S.
Tey, Dean
Su, Ee Lyn
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Publisher
John Wiley & Sons, Inc.
Published Version
Research Projects
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Abstract
There are few data on long-term effects and quality of life impact of peanut OIT. PPOIT was shown to induce 8-week sustained unresponsiveness that persists to 3-years post-treatment after ad libitum peanut ingestion. PPOIT provides lasting benefits for children with peanut allergy, with long-lasting improvement in health-related quality of life.
Description
Research Letter
Keywords
Peanut allergy , Health-related quality of life , Oral immunotherapy , Probiotic , Sustained unresponsiveness
Citation
Loke, P., Hsiao, K.-C., Chebar Lozinsky, A., Ashley, S. E., Lloyd, M., Pitkin, S., Axelrad, C. J., Jayawardana, K. S., Tey, D., Su, E. L., Robinson, M., Leung, A. S., Dunn Galvin, A. and Tang, M. L. K. (2022) 'Probiotic peanut oral immunotherapy is associated with long-term persistence of 8-week sustained unresponsiveness and long-lasting quality-of-life improvement', Clinical and Experimental Allergy. doi: 10.1111/cea.14137
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Copyright
© 2022, John Wiley & Sons, Ltd. This is the peer reviewed version of the following article: Loke, P., Hsiao, K.-C., Chebar Lozinsky, A., Ashley, S. E., Lloyd, M., Pitkin, S., Axelrad, C. J., Jayawardana, K. S., Tey, D., Su, E. L., Robinson, M., Leung, A. S., Dunn Galvin, A. and Tang, M. L. K. (2022) 'Probiotic peanut oral immunotherapy is associated with long-term persistence of 8-week sustained unresponsiveness and long-lasting quality-of-life improvement', Clinical and Experimental Allergy, doi: 10.1111/cea.14137, which has been published in final form at: https://doi.org/10.1111/cea.14137. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.