APPEAL‐1: A pan-European survey of patient/caregiver perceptions of peanut allergy management

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dc.contributor.authorBlumchen, Katharina
dc.contributor.authorDunn Galvin, Audrey
dc.contributor.authorTimmermans, Frans
dc.contributor.authorRegent, Lynne
dc.contributor.authorSchnadt, Sabine
dc.contributor.authorPodestà, Marcia
dc.contributor.authorSánchez, Angel
dc.contributor.authorCouratier, Pascale
dc.contributor.authorFeeney, Mary
dc.contributor.authorHjorth, Betina
dc.contributor.authorPatel, Ram
dc.contributor.authorLush, Tessa
dc.contributor.authorRyan, Robert
dc.contributor.authorVereda, Andrea
dc.contributor.authorFisher, Helen R.
dc.contributor.authorFernández-Rivas, Montserrat
dc.contributor.funderAimmune Therapeutics, United Statesen
dc.date.accessioned2020-05-27T10:40:18Z
dc.date.available2020-05-27T10:40:18Z
dc.date.issued2020-05-21
dc.description.abstractBackground: Peanut allergy (PA) is associated with marked quality‐of‐life (QoL) impairment. However, data are lacking on the experience and impact of living with PA from the perspectives of persons with PA (PwPA) and their caregivers. A llergy to P eanuts imP acting E motions A nd L ife study 1 (APPEAL‐1) was a pan‐European survey investigating these perspectives. This first of two articles reports clinical characteristics of PwPA and PA management practices. Methods: APPEAL‐1 was a quantitative, online survey conducted in eight European countries, developed by eight representatives of patient advocacy groups and five healthcare professionals and researchers. Eligible participants included adults with PA and parents/caregivers of PwPA who responded by self‐report and provided proxy‐report for the PwPA under their care. Data were summarised using nonweighted descriptive statistics. Results: Of 1846 completed/analysed questionnaires, 528 were from adults with PA (self‐report); 437 by proxy for children with PA (34 aged 0‐3 years, 287 aged 4‐12 years, 116 aged 13‐17 years); 881 from parents/caregivers (self‐report). Of PwPA (N=965), 95% reported diagnosis by healthcare professionals, mostly by clinical history and peanut‐specific allergy testing. Rates of allergic rhinitis, asthma, and other food allergies in PwPA were 50%, 42%, and 79%, respectively. Only 31% of PwPA received HCP advice/support following their worst allergic reaction, and 28% had not been prescribed an adrenaline auto‐injector. Results were similar by country but varied by age group. Conclusions: The APPEAL‐1 findings contribute to greater understanding of PA impact on PwPA, caregivers, and family members and the need for improved PA management across Europe.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationBlumchen, K., Dunn Galvin, A., Timmermans, F., Regent, L., Schnadt, S., Podestà, M., Sánchez, A., Couratier, P., Feeney, M., Hjorth, B., Patel, R., Lush, T., Ryan, R., Vereda, A., Fisher, H.R. and Fernández‐Rivas, M. (2020) ‘APPEAL‐1: A pan-European survey of patient/caregiver perceptions of peanut allergy management’, Allergy, 75(11), pp. 2920–2935. doi: 10.1111/all.14414en
dc.identifier.doi10.1111/all.14414en
dc.identifier.eissn1398-9995
dc.identifier.endpage2935
dc.identifier.issn0105-4538
dc.identifier.issued11
dc.identifier.journaltitleAllergyen
dc.identifier.startpage2920
dc.identifier.urihttps://hdl.handle.net/10468/10065
dc.identifier.volume75
dc.language.isoenen
dc.publisherJohn Wiley & Sons, Inc.en
dc.rights© 2020, the Authors. Allergy published by European Academy of Allergy and Clinical Immunology and John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproductionin any medium, provided the original work is properly cited and is not used for commercial purposes.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/
dc.subjectClinical historyen
dc.subjectDiagnosisen
dc.subjectEuropeen
dc.subjectPeanut allergyen
dc.subjectQuality of lifeen
dc.titleAPPEAL‐1: A pan-European survey of patient/caregiver perceptions of peanut allergy managementen
dc.typeArticle (peer-reviewed)en
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