Heart rate variability during periods of low blood pressure as a predictor of short-term outcome in preterms

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dc.contributor.authorSemenova, Oksana
dc.contributor.authorCarra, Giorgia
dc.contributor.authorLightbody, Gordon
dc.contributor.authorBoylan, Geraldine B.
dc.contributor.authorDempsey, Eugene M.
dc.contributor.authorTemko, Andriy
dc.contributor.funderScience Foundation Irelanden
dc.date.accessioned2021-08-26T09:27:01Z
dc.date.available2021-08-26T09:27:01Z
dc.date.issued2018-10-29
dc.date.updated2021-08-26T09:17:28Z
dc.description.abstractEfficient management of low blood pressure (BP) in preterm neonates remains challenging with a considerable variability in clinical practice. The ability to assess preterm wellbeing during episodes of low BP will help to decide when and whether hypotension treatment should be initiated. This work aims to investigate the relationship between heart rate variability (HRV), BP and the short-term neurological outcome in preterm infants less than 32 weeks gestational age (GA). The predictive power of common HRV features with respect to the outcome is assessed and shown to improve when HRV is observed during episodes of low mean arterial pressure (MAP) - with a single best feature leading to an AUC of 0.87. Combining multiple features with a boosted decision tree classifier achieves an AUC of 0.97. The work presents a promising step towards the use of multimodal data in building an objective decision support tool for clinical prediction of short-term outcome in preterms who suffer episodes of low BP.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationSemenova, O., Carra, G., Lightbody, G., Boylan, G., Dempsey, E. and Temko, A. (2018) 'Heart rate variability during periods of low blood pressure as a predictor of short-term outcome in preterms', 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), Honolulu, HI, USA, 18-21 August, pp. 5614-5617. doi: 10.1109/EMBC.2018.8513600en
dc.identifier.doi10.1109/EMBC.2018.8513600en
dc.identifier.eissn1558-4615
dc.identifier.endpage5617en
dc.identifier.isbn978-1-5386-3646-6
dc.identifier.isbn978-1-5386-3645-9
dc.identifier.isbn978-1-5386-3647-3
dc.identifier.issn1557-170X
dc.identifier.startpage5614en
dc.identifier.urihttps://hdl.handle.net/10468/11790
dc.language.isoenen
dc.publisherInstitute of Electrical and Electronics Engineers (IEEE)en
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2272/IE/Irish Centre for Fetal and Neonatal Translational Research (INFANT)/en
dc.rights© 2018, IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.en
dc.subjectHeart rate variabilityen
dc.subjectPediatricsen
dc.subjectBlood pressureen
dc.subjectDecision treesen
dc.subjectElectrocardiographyen
dc.subjectFeature extractionen
dc.subjectFrequency-domain analysisen
dc.titleHeart rate variability during periods of low blood pressure as a predictor of short-term outcome in pretermsen
dc.typeConference itemen
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