Navigational bronchoscopy for early lung cancer: a road to therapy

dc.contributor.authorKhan, Kashif Ali
dc.contributor.authorNardelli, Pietro
dc.contributor.authorJaeger, Herman Alexander
dc.contributor.authorO'Shea, Conor
dc.contributor.authorCantillon-Murphy, Pádraig
dc.contributor.authorKennedy, Marcus P.
dc.date.accessioned2019-09-06T09:08:36Z
dc.date.available2019-09-06T09:08:36Z
dc.date.issued2016-03-22
dc.date.updated2019-09-05T15:49:15Z
dc.description.abstractPeripheral lung nodules remain challenging for accurate localization and diagnosis. Once identified, there are many strategies for diagnosis with heterogeneous risk benefit analysis. Traditional strategies such as conventional bronchoscopy have poor performance in locating and acquiring the required tissue. Similarly, while computerized-assisted transthoracic needle biopsy is currently the favored diagnostic procedure, it is associated with complications such as pneumothorax and hemorrhage. Video-assisted thoracoscopic and open surgical biopsies are invasive, require general anesthesia and are therefore not a first-line approach. New techniques such as ultrathin bronchoscopy and image-based guidance technologies are evolving to improve the diagnosis of peripheral lung lesions. Virtual bronchoscopy and electromagnetic navigation systems are novel technologies based on assisted-computerized tomography images that guide the bronchoscopist toward the target peripheral lesion. This article provides a comprehensive review of these emerging technologies.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationKhan, K. A., Nardelli, P., Jaeger, A., O’Shea, C., Cantillon-Murphy, P. and Kennedy, M. P. (2016) 'Navigational Bronchoscopy for Early Lung Cancer: A Road to Therapy', Advances in Therapy, 33(4), pp. 580-596. doi: 10.1007/s12325-016-0319-4en
dc.identifier.doi10.1007/s12325-016-0319-4en
dc.identifier.endpage596en
dc.identifier.issn1865-8652
dc.identifier.issued4en
dc.identifier.journaltitleAdvances in Therapyen
dc.identifier.startpage580en
dc.identifier.urihttps://hdl.handle.net/10468/8460
dc.identifier.volume33en
dc.language.isoenen
dc.publisherSpringeren
dc.relation.urihttps://link.springer.com/article/10.1007%2Fs12325-016-0319-4
dc.rights© The Author(s) 2016. This article is published with open access at Springerlink.com. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0), which permits use, duplication, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0en
dc.subjectBronchoscopyen
dc.subjectComputerized tomography (CT)en
dc.subjectElectromagnetic navigationen
dc.subjectImage guidanceen
dc.subjectLung canceren
dc.subjectPeripheral lung lesionen
dc.subjectRespiratoryen
dc.titleNavigational bronchoscopy for early lung cancer: a road to therapyen
dc.typeArticle (peer-reviewed)en
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