Planning, implementing, and running a multicentre preterm birth study with biobank resources in Brazil: The preterm SAMBA study

Simple item page
dc.contributor.authorSouza, Renato T.
dc.contributor.authorCecatti, Jose G.
dc.contributor.authorCosta, Maria L.
dc.contributor.authorMayrink, Jussara
dc.contributor.authorPacagnella, Rodolfo C.
dc.contributor.authorPassini Jr, Renato
dc.contributor.authorFranchini, Kleber G.
dc.contributor.authorFeitosa, Francisco E.
dc.contributor.authorCalderon, Iracema M.
dc.contributor.authorRocha Filho, Edilberto A.
dc.contributor.authorLeite, Débora F.
dc.contributor.authorVettorazzi, Janete
dc.contributor.authorKenny, Louise C.
dc.contributor.authorBaker, Philip N.
dc.contributor.authorThe Preterm SAMBA Study Group
dc.date.accessioned2019-03-11T12:37:50Z
dc.date.available2019-03-11T12:37:50Z
dc.date.issued2018
dc.description.abstractOur aim was to describe the steps in planning, implementing, and running a multicentre cohort study of maternal and perinatal health using a high-quality biobank comprised of maternal serum, plasma, and hair samples collected from five sites in Brazil. The Preterm SAMBA study, conducted by the Brazilian Network for Studies on Reproductive and Perinatal Health, was an innovative approach used to identify women at higher risk for preterm birth. It is also of great importance in the study of other maternal and perinatal complications in the context of Brazil, which is a middle-income country. Methods. We described phases of planning, implementing, and running the Preterm SAMBA study, a multicentre Brazilian cohort study of low-risk nulliparous pregnant women, to validate a set of metabolite biomarkers for preterm birth identified in an external cohort. Procedures and strategies used to plan, implement, and maintain this multicentre preterm birth study are described in detail. Barriers and experience cited in the current narrative are not usually discussed in the scientific literature or published study protocols. Results. Several barriers and strategies were identified in different phases of the Preterm SAMBA study at different levels of the study framework (steering committee; coordinating and local centres). Strategies implemented and resources used in the study are a legacy of the Brazilian Network, aimed at training collaborators in such complex settings. Conclusion. The Brazilian Network for Studies on Reproductive and Perinatal Health has gained some experience in conducting a multicentre cohort study using a resourceful biobank which may be helpful to other research groups and maternal/perinatal health networks that plan on employing a similar approach to a similar background.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid5476350
dc.identifier.citationSouza, R.T., Cecatti, J.G., Costa, M.L., Mayrink, J., Pacagnella, R.C., Passini, R., Franchini, K.G., Feitosa, F.E., Calderon, I.M., Rocha Filho, E.A. and Leite, D.F., 2019. Planning, Implementing, and Running a Multicentre Preterm Birth Study with Biobank Resources in Brazil: The Preterm SAMBA Study. BioMed Research International, 2019, 5476350 (8pp.) DOI:10.1155/2019/5476350en
dc.identifier.doi10.1155/2019/5476350
dc.identifier.endpage8en
dc.identifier.issn2314-6133
dc.identifier.journaltitleBioMed Research Internationalen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/7599
dc.identifier.volume2019en
dc.language.isoenen
dc.publisherHindawien
dc.relation.urihttps://www.hindawi.com/journals/bmri/2019/5476350/abs/
dc.rights© 2019 Renato T. Souza et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectPreterm birth studyen
dc.subjectPublic healthen
dc.subjectAntenatal careen
dc.titlePlanning, implementing, and running a multicentre preterm birth study with biobank resources in Brazil: The preterm SAMBA studyen
dc.typeArticle (peer-reviewed)en
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
5476350 (1).pdf
Size:
1.67 MB
Format:
Adobe Portable Document Format
Description:
Published Version
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
INFANT Research Centre - Journal Articles