Phenomenology and epidemiology of impulsive-compulsive behaviours in Parkinson's disease, atypical Parkinsonian disorders and non-Parkinsonian populations
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Accepted version
Date
2017-12-28
Authors
Maloney, Eimer M.
Djamshidian, Atbin
O'Sullivan, Sean S.
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Published Version
Abstract
Impulsive-compulsive behaviours are common, quality of life affecting consequences of dopamine replacement therapy which are well recognized in patients with idiopathic Parkinson's disease. Details of the occurrence and nature of these disorders in the atypical parkinsonian neurodegenerative disorders, and in non-Parkinson's patients prescribed dopaminergic stimulation for other disease processes, are slowly emerging. Here we review what is known about the phenomenology, epidemiology and risk factors for impulsive-compulsive behaviours in Parkinson's disease and in other, less well studied, patient groups. By analyzing the available published data, this review identifies potential clues as to the underlying neurobiological mechanism of these disorders, and further identifies critical gaps yet to be addressed.
Description
Keywords
Parkinson's disease , Impulse control disorders , Impulsive-compulsive behaviours , Atypical Parkinson's , Dopaminergic medication
Citation
Maloney, E. M., Djamshidian, A. and O'Sullivan, S. S. (2017) 'Phenomenology and epidemiology of impulsive-compulsive behaviours in Parkinson's disease, atypical Parkinsonian disorders and non-Parkinsonian populations', Journal of the Neurological Sciences, 374, pp. 47-52. doi: 10.1016/j.jns.2016.12.058