The association between the maternal diet and the maternal and infant gut microbiome: A systematic review

Simple item page
dc.contributor.authorMaher, Siofra E.
dc.contributor.authorO'Brien, Eileen C.
dc.contributor.authorMoore, Rebecca L.
dc.contributor.authorByrne, David F.
dc.contributor.authorGeraghty, Aisling A.
dc.contributor.authorSaldova, Radka
dc.contributor.authorMurphy, Eileen F.
dc.contributor.authorvan Sinderen, Douwe
dc.contributor.authorCotter, Paul D.
dc.contributor.authorMcAuliffe, Fionnuala M.
dc.contributor.funderScience Foundation Irelanden
dc.contributor.funderAlimentary Healthen
dc.date.accessioned2021-10-01T10:30:30Z
dc.date.available2021-10-01T10:30:30Z
dc.date.issued2020-03-04
dc.date.updated2021-09-29T15:02:38Z
dc.description.abstractDuring pregnancy, changes occur to influence the maternal gut microbiome, and potentially the fetal microbiome. Diet has been shown to impact the gut microbiome. Little research has been conducted examining diet during pregnancy with respect to the gut microbiome. To meet inclusion criteria, dietary analyses must have been conducted as part of the primary aim. The primary outcome was the composition of the gut microbiome (infant or maternal), as assessed using culture-independent sequencing techniques. This review identified seven studies for inclusion, five examining the maternal gut microbiome and two examining the fetal gut microbiome. Microbial data were attained through analysis of stool samples by 16S rRNA gene-based microbiota assessment. Studies found an association between the maternal diet and gut microbiome. High-fat diets (% fat of total energy), fat-soluble vitamins (mg/day) and fibre (g/day) were the most significant nutrients associated with the gut microbiota composition of both neonates and mothers. High-fat diets were significantly associated with a reduction in microbial diversity. High-fat diets may reduce microbial diversity, while fibre intake may be positively associated with microbial diversity. The results of this review must be interpreted with caution. The number of studies was low, and the risk of observational bias and heterogeneity across the studies must be considered. However, these results show promise for dietary intervention and microbial manipulation in order to favour an increase of health-associated taxa in the gut of the mother and her offspring.en
dc.description.sponsorshipScience Foundation Ireland (16/SP/3827)en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationMaher, S. E., O'Brien, E. C., Moore, R. L., Byrne, D. F., Geraghty, A. A., Saldova, R., Murphy, E. F., Van Sinderen, D., Cotter, P. D. and McAuliffe, F. M. (2020) 'The association between the maternal diet and the maternal and infant gut microbiome: A systematic review', British Journal of Nutrition, pp. 1-29. doi: 10.1017/S0007114520000847en
dc.identifier.doi10.1017/S0007114520000847en
dc.identifier.eissn1475-2662
dc.identifier.endpage29en
dc.identifier.issn0007-1145
dc.identifier.journaltitleBritish Journal of Nutritionen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/12039
dc.language.isoenen
dc.publisherCambridge University Pressen
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2273/IE/Alimentary Pharmabiotic Centre (APC) - Interfacing Food & Medicine/en
dc.rights© 2020, the Authors. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectDieten
dc.subjectGut microbiomeen
dc.subjectInfant microbiomeen
dc.subjectMaternal microbiomeen
dc.subjectNutritionen
dc.subjectPregnancyen
dc.titleThe association between the maternal diet and the maternal and infant gut microbiome: A systematic reviewen
dc.typeArticle (peer-reviewed)en
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
the-association-between-the-maternal-diet-and-the-maternal-and-infant-gut-microbiome-a-systematic-review.pdf
Size:
1.17 MB
Format:
Adobe Portable Document Format
Description:
Accepted Version
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
APC Microbiome Ireland - Journal Articles
Microbiology - Journal Articles