Electrochemical sensor interface

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Murphy, Aidan
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University College Cork
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Recent advances in nanotechnology have led to the development of electrochemical sensors that utilize electrodes with a width of one micron or less. This increased sensitivity has opened up a range of new electrochemical sensing applications, allowing the technology to move beyond the confines of the laboratory and into real-world settings. However, the interfacial electronics used for these sensors are often too bulky for portable use and can be prohibitively expensive due to the low current measurement capability required from the instrument. To address this challenge, this thesis presents cost-effective measures for creating portable interfaces specifically designed for ultra-micro and nano-scale electrochemical sensors. A portable data acquisition system has been developed to interface to nano and ultra-micro scale electrochemical sensors at the point of use through voltammetry. It can perform a range of voltammetric tests, including cyclic voltammetry, square wave voltammetry and generator collector voltammetry. The data acquisition system interfaces to a smartphone, operates from a rechargeable battery and is of suitable form factor to ensure that it’s fully portable. By utilising commercially available components, this system has been developed to lower the barrier for entry for the development of emerging portable electrochemical sensing technologies at micro and nano scale. A second data acquisition system has been developed to interface to nano and ultra micro electrochemical immunosensors through Electrochemical Impedance Spectroscopy. Results from the device were benchmarked against laboratory equipment to ensure it is of suitable sensitivity to be fit for purpose. The printed circuit board has been designed such that it can be integrated into a handheld device suitable for operatives such as veterinarians. This system will aid in the detection of biological agents such as viruses and antibodies at the point of sample, particularly in electrochemical sensors designed for agricultural applications.
Potentiostat , Biosensor , Voltammetry , EIS , Impedance
Murphy, A. 2023. Electrochemical sensor interface. PhD Thesis, University College Cork.
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