Lactobacillus rossiae, a vitamin B12 producer, represents a metabolically versatile species within the genus Lactobacillus

dc.contributor.authorDe Angelis, Maria
dc.contributor.authorBottacini, Francesca
dc.contributor.authorFosso, Bruno
dc.contributor.authorKelleher, Philip
dc.contributor.authorCalasso, Maria
dc.contributor.authorDi Cagno, Raffaella
dc.contributor.authorVentura, Marco
dc.contributor.authorPicardi, Ernesto
dc.contributor.authorvan Sinderen, Douwe
dc.contributor.authorGobbetti, Marco
dc.date.accessioned2016-02-17T11:43:38Z
dc.date.available2016-02-17T11:43:38Z
dc.date.issued2014
dc.description.abstractLactobacillus rossiae is an obligately hetero-fermentative lactic acid bacterium, which can be isolated from a broad range of environments including sourdoughs, vegetables, fermented meat and flour, as well as the gastrointestinal tract of both humans and animals. In order to unravel distinctive genomic features of this particular species and investigate the phylogenetic positioning within the genus Lactobacillus, comparative genomics and phylogenomic approaches, followed by functional analyses were performed on L. rossiae DSM 15814(T), showing how this type strain not only occupies an independent phylogenetic branch, but also possesses genomic features underscoring its biotechnological potential. This strain in fact represents one of a small number of bacteria known to encode a complete de novo biosynthetic pathway of vitamin B-12 (in addition to other B vitamins such as folate and riboflavin). In addition, it possesses the capacity to utilize an extensive set of carbon sources, a characteristic that may contribute to environmental adaptation, perhaps enabling the strain's ability to populate different niches.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleide107232
dc.identifier.citationDe Angelis M, Bottacini F, Fosso B, Kelleher P, Calasso M, Di Cagno R, et al. (2014) Lactobacillus rossiae, a Vitamin B12 Producer, Represents a Metabolically Versatile Species within the Genus Lactobacillus. PLoS ONE 9(9): e107232. doi:10.1371/journal.pone.0107232
dc.identifier.doi10.1371/journal.pone.0107232
dc.identifier.issn1932-6203
dc.identifier.issued9en
dc.identifier.journaltitlePLOS ONEen
dc.identifier.urihttps://hdl.handle.net/10468/2323
dc.identifier.volume9en
dc.language.isoenen
dc.publisherPublic Library of Scienceen
dc.rights© 2015 De Angelis et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are crediteden
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/en
dc.subjectLactic acid bacteriaen
dc.subjectComparative genome analysisen
dc.subjectSourdoughen
dc.subjectSequenceen
dc.subjectSanfranciscensisen
dc.subjectEthanolamineen
dc.subjectPlantarumen
dc.subjectReuterien
dc.subjectWheaten
dc.subjectMicrobiotaen
dc.titleLactobacillus rossiae, a vitamin B12 producer, represents a metabolically versatile species within the genus Lactobacillusen
dc.typeArticle (peer-reviewed)en
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