Atraumatic vs conventional restorative treatment for root caries lesions in older patients: Meta‐ and trial sequential analysis

Simple item page
dc.contributor.authorGöstemeyer, Gerden
dc.contributor.authorda Mata, Cristianeen
dc.contributor.authorMcKenna, Geralden
dc.contributor.authorSchwendicke, Falken
dc.date.accessioned2024-01-16T11:43:15Z
dc.date.available2024-01-16T11:43:15Z
dc.date.issued2019-05-24en
dc.description.abstractObjectives: We aimed to appraise the comparative clinical efficacy of atraumatic restorative treatment (ART) versus conventional restorative treatment (CT) using a meta-analysis, and assessed the robustness of evidence by trial sequential analysis (TSA). Background: Due to its simplified clinical approach, ART may be advantageous over CT for restoration of root caries lesions in institutionalised older patients. Methods: Three electronic databases (PubMed, Embase and Cochrane CENTRAL) were screened, and hand searches and cross-referencing performed to identify randomised controlled trials reporting on survival of ART vs CT for restoration of root caries in older patients. Trial selection, data extraction and risk of bias assessment were performed by two independent reviewers. ART and CT were compared using fixed- or random-effects pairwise meta-analysis for per-protocol (PP), intention-to-treat (ITT) and best-case scenarios. TSA was used to control for risk of random errors. Results: A total of 235 studies were identified, and three trials involving 130 patients (463 restorations) were included. Risk of bias was high or moderate in all but one trial. ART was associated with a significantly increased risk of failure (OR [95% CI] 2.06 [1.06/4.00]) in PP- but not in ITT analysis (1.36 [0.92/2.02]). Analyses for best-case scenarios found great uncertainty introduced by attrition. No firm evidence was reached according to TSA. Conclusions: For restoration of root caries, there is insufficient data to clearly rule out whether differences between ART and CT exist. Limited available data indicate there might be an increased risk of failure for ART.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationGöstemeyer, G., da Mata, C., McKenna, G. and Schwendicke, F. (2019) 'Atraumatic vs conventional restorative treatment for root caries lesions in older patients: Meta- and trial sequential analysis', Gerodontology, 36(3), pp. 285-293. https://doi.org/10.1111/ger.12409en
dc.identifier.doihttps://doi.org/10.1111/ger.12409en
dc.identifier.eissn1741-2358en
dc.identifier.endpage293en
dc.identifier.issn0734-0664en
dc.identifier.issued3en
dc.identifier.journaltitleGerodontologyen
dc.identifier.startpage285en
dc.identifier.urihttps://hdl.handle.net/10468/15379
dc.identifier.volume36en
dc.language.isoenen
dc.publisherJohn Wiley & Sons, Inc.en
dc.rights© 2019, Gerodontology Association and John Wiley & Sons Ltd. This is the accepted version of the following item: Göstemeyer, G., da Mata, C., McKenna, G. and Schwendicke, F. (2019) 'Atraumatic vs conventional restorative treatment for root caries lesions in older patients: Meta- and trial sequential analysis', Gerodontology, 36(3), pp. 285-293, which has been published in final form at: https://doi.org/10.1111/ger.12409. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.en
dc.subjectAtraumatic restorative treatmenten
dc.subjectEvidence‐based dentistryen
dc.subjectGeriatric dentistryen
dc.subjectRoot cariesen
dc.titleAtraumatic vs conventional restorative treatment for root caries lesions in older patients: Meta‐ and trial sequential analysisen
dc.typeArticle (peer-reviewed)en
oaire.citation.issue3en
oaire.citation.volume36en
Files
Original bundle
Now showing 1 - 2 of 2
Thumbnail Image
Name:
REstorative.pdf
Size:
1.04 MB
Format:
Adobe Portable Document Format
Description:
Accepted Version
Download
Thumbnail Image
Name:
ger12409-sup-0001-supinfo.docx
Size:
2.36 MB
Format:
Microsoft Word XML
Description:
Supporting Information
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
2.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Cork University Dental School and Hospital - Journal Articles