An ultrasonically-powered system for 1.06mm3 implantable optogenetics and drug delivery dust
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Date
2023-06-23
Authors
Laursen, Kjeld
Zamani, Milad
Rezaeiyan, Yasser
Hosseini, Seyedsina
Mondal, Tanmay
Corbett, Brian
Ouagazzal, Abdel Mouttalib
Amalric, Marianne
Moradi, Farshad
Journal Title
Journal ISSN
Volume Title
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Published Version
Abstract
This paper presents an ultrasonically powered micro-system for deep tissue optogenetic stimulation. The developed system is composed of a Base for Powering and Controlling (BPC) and an implantable Dust for optogenetics and drug delivery. The Dust consists of a piezoelectric crystal, a rectifier chip, and a micro-scale custom-designed light-emitting-diode (μLED) integrated, miniaturized, and envisioned to be used for freely moving animal studies. The proposed Dust operates in frequencies up to 5 MHz, power levels in the 0–10 mW range, achieves start-up within 1.8 μs at 2.9 MHz operating frequency at 14.4 mW/mm2 ultrasound power density, and 98.1% chip efficiency at 2 mW input power. With the BPC implemented and attached to (500 μm)3 PZT4 crystals, set to 60 V at 2.8 MHz operating frequency at 3 mm distance in demineralized water, the dust delivered up to 6 mW to its load (μLED for optogenetics), which translates to 0.11% total system efficiency.
Description
Keywords
Dust , Optogenetic stimulation , Rectifier , Piezoelectric , Ultrasonic power transfer
Citation
Laursen, K., Zamani, M., Rezaeiyan, Y., Hosseini, S., Mondal, T., Corbett, B., Ouagazzal, A. M., Amalric, M. and Moradi, F. (2023) 'An ultrasonically-powered system for 1.06 mm3 implantable optogenetics and drug delivery dust', IEEE Transactions on Circuits and Systems II: Express Briefs, 70(10), pp, 3937-3941. doi: 10.1109/TCSII.2023.3289028
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