A cost minimisation analysis of NOACs compared to warfarin to attain therapeutic anticoagulation amongst AF patients, pre- and post-cardioversion

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Date
2016-11
Authors
O'Shea, M.
Murphy, Aileen
Kirby, Ann
Allen, G.
O'Shea, S.
Curtin, R.
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Volume Title
Publisher
Irish Medical Organisation
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Research Projects
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Abstract
Atrial fibrillation can be managed with anticoagulation and restoration of normal sinus rhythm using direct current cardioversion (DCCV). To reduce the risk of thromboembolism anticoagulation pre-and-post DCCV is recommended. This study investigates the cost effectiveness of using NOACs compared to warfarin to attain therapeutic anticoagulation amongst AF patients pre-and-post DCCV. Propensity score matching revealed no statistically significant difference in outcomes from using NOACs and Warfarin. A cost minimisation study was performed; demonstrating a cost differential of €209 between those administered NOACs and warfarin pre and post DCCV. This study demonstrates how using NOACs compared to warfarin to attain therapeutic anticoagulation amongst AF patients preand-post DCCV is cost effective.
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Keywords
Anticoagulants , Medicines , Heart disease
Citation
O'Shea, M., Murphy, A., Kirby, A., Allen, G., O'Shea, S. and Curtin, R. (2016) 'A cost minimisation analysis of NOACs compared to warfarin to attain therapeutic anticoagulation amongst AF patients, pre- and post-cardioversion', Irish Medical Journal, 109(10), 480 (7pp).
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© 2016, Irish Medical Journal. All rights reserved.