Pilot-scale ceramic membrane filtration of skim milk for the production of a 'humanised' protein base ingredient for infant milk formula

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dc.check.date2018-05-08
dc.check.infoAccess to this article is restricted until 12 months after publication by request of the publisher.en
dc.contributor.authorMcCarthy, Noel A.
dc.contributor.authorWijayanti, Heni B.
dc.contributor.authorCrowley, Shane V.
dc.contributor.authorO'Mahony, James A.
dc.contributor.authorFenelon, Mark A.
dc.contributor.funderDepartment of Agriculture, Food and the Marineen
dc.date.accessioned2017-08-31T12:14:29Z
dc.date.available2017-08-31T12:14:29Z
dc.date.issued2017-05-08
dc.date.updated2017-08-31T11:07:53Z
dc.description.abstractThe protein composition of bovine skim milk was modified using pilot scale membrane filtration to produce a whey protein-dominant ingredient with a casein profile closer to human milk. Bovine skim milk was processed at low (8.9 °C) or high (50 °C) temperature using ceramic microfiltration (MF) membranes (0.1 μm mean pore diameter). The resulting permeate stream was concentrated using polyethersulfone ultrafiltration (UF) membranes (10 kDa cut-off). The protein profile of MF and UF retentate streams were determined using reversed phase-high performance liquid chromatography and polyacrylamide gel electrophoresis. Permeate from the cold MF process (8.9 °C) had a casein:whey protein ratio of ∼35:65 with no αS- or κ-casein present, compared with a casein:whey protein ratio of ∼10:90 at 50 °C. This study has demonstrated the application of cold membrane filtration (8.9 °C) at pilot scale to produce a dairy ingredient with a protein profile closer to that of human milk.en
dc.description.sponsorshipDepartment of Agriculture, Food and the Marine (Project Reference Number 10RDTMFRC706)en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationMcCarthy, N. A., Wijayanti, H. B., Crowley, S. V., O'Mahony, J. A., and Fenelon, M. A. (2017) 'Pilot-scale ceramic membrane filtration of skim milk for the production of a 'humanised' protein base ingredient for infant milk formula', International Dairy Journal, 73, pp. 57-62. doi:10.1016/j.idairyj.2017.04.010en
dc.identifier.doi10.1016/j.idairyj.2017.04.010
dc.identifier.endpage62en
dc.identifier.issn0958-6946
dc.identifier.journaltitleInternational Dairy Journalen
dc.identifier.startpage57en
dc.identifier.urihttps://hdl.handle.net/10468/4596
dc.identifier.volume73en
dc.language.isoenen
dc.publisherElsevier Ltden
dc.rights© 2017, Published by Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license.en
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectProteinen
dc.subjectHuman milken
dc.subjectFiltrationen
dc.titlePilot-scale ceramic membrane filtration of skim milk for the production of a 'humanised' protein base ingredient for infant milk formulaen
dc.typeArticle (peer-reviewed)en
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