Herpetic tracheitis in association with rituximab therapy

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dc.contributor.authorThong, Lorraine
dc.contributor.authorPlant, Barry J.
dc.contributor.authorMcCarthy, Julie
dc.contributor.authorMurphy, Desmond M.
dc.date.accessioned2017-01-23T10:21:02Z
dc.date.available2017-01-23T10:21:02Z
dc.date.issued2016-05-05
dc.date.updated2017-01-23T10:12:25Z
dc.description.abstractA 58-year old lady under active follow-up with the respiratory services at our institution for bronchiectasis secondary to hypogammaglobulinaemia presented with hoarseness and haemoptysis. She was also receiving rituximab maintenance therapy for follicular lymphoma. Bronchoscopy demonstrated vesicular lesions on her vocal cords and trachea, confirmed as herpes simplex virus (HSV) on cytological analysis of brushings. She responded well to intravenous valacyclovir. Rituximab is increasingly utilised in the treatment of haematological and auto-immune disorders. This case highlights the potential of this drug to potentiate susceptibility to infection in an already immunocompromised individual.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationThong, L., Plant, B. J., McCarthy, J. and Murphy, D. M. (2016) 'Herpetic tracheitis in association with rituximab therapy', Respirology Case Reports, 4(4), e00158. doi:10.1002/rcr2.158en
dc.identifier.doi10.1002/rcr2.158
dc.identifier.endpagee00158-3en
dc.identifier.issn2051-3380
dc.identifier.issued4en
dc.identifier.journaltitleRespirology Case Reportsen
dc.identifier.startpagee00158-1en
dc.identifier.urihttps://hdl.handle.net/10468/3497
dc.identifier.volume4en
dc.language.isoenen
dc.publisherWileyen
dc.rights© 2016 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.en
dc.rights.urihttps://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectHerpes simplexen
dc.subjectImmunosuppressionen
dc.subjectNon-Hodgkin's lymphomaen
dc.subjectRituximaben
dc.subjectTracheitisen
dc.titleHerpetic tracheitis in association with rituximab therapyen
dc.typeArticle (peer-reviewed)en
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