Dietary supplementation with a magnesium-rich marine mineral blend enhances the diversity of gastrointestinal microbiota

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dc.contributor.authorCrowley, Erin K.
dc.contributor.authorLong-Smith, Caitriona M.
dc.contributor.authorMurphy, Amy
dc.contributor.authorPatterson, Elaine
dc.contributor.authorMurphy, Kiera
dc.contributor.authorO'Gorman, Denise M.
dc.contributor.authorStanton, Catherine
dc.contributor.authorNolan, Yvonne M.
dc.contributor.funderScience Foundation Ireland
dc.contributor.funderSeventh Framework Programme
dc.date.accessioned2018-09-20T15:53:44Z
dc.date.available2018-09-20T15:53:44Z
dc.date.issued2018
dc.description.abstractAccumulating evidence demonstrates that dietary supplementation with functional food ingredients play a role in systemic and brain health as well as in healthy ageing. Conversely, deficiencies in calcium and magnesium as a result of the increasing prevalence of a high fat/high sugar Western diet have been associated with health problems such as obesity, inflammatory bowel diseases, and cardiovascular diseases, as well as metabolic, immune, and psychiatric disorders. It is now recognized that modulating the diversity of gut microbiota, the population of intestinal bacteria, through dietary intervention can significantly impact upon gut health as well as systemic and brain health. In the current study, we show that supplementation with a seaweed and seawater-derived functional food ingredient rich in bioactive calcium and magnesium (0.1% supplementation) as well as 70 other trace elements, significantly enhanced the gut microbial diversity in adult male rats. Given the significant impact of gut microbiota on health, these results position this marine multi-mineral blend (MMB) as a promising digestive-health promoting functional food ingredient.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid216
dc.identifier.citationCrowley, E., Long-Smith, C., Murphy, A., Patterson, E., Murphy, K., O’Gorman, D., Stanton, C. and Nolan, Y. (2018) 'Dietary supplementation with a magnesium-rich marine mineral blend enhances the diversity of gastrointestinal microbiota', Marine Drugs, 16(6), 216 (13pp). doi: 10.3390/md16060216en
dc.identifier.doi10.3390/md16060216
dc.identifier.endpage13
dc.identifier.issn1660-3397
dc.identifier.issued6
dc.identifier.journaltitleMarine Drugsen
dc.identifier.startpage1
dc.identifier.urihttps://hdl.handle.net/10468/6839
dc.identifier.volume16
dc.language.isoenen
dc.publisherMDPIen
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Research Centres/12/RC/2273/IE/Alimentary Pharmabiotic Centre (APC) - Interfacing Food & Medicine/
dc.relation.projectinfo:eu-repo/grantAgreement/EC/FP7::SP1::KBBE/613979/EU/Microbiome Influence on Energy balance and Brain Development-Function Put into Action to Tackle Diet-related Diseases and Behavior./MYNEWGUT
dc.relation.projectinfo:eu-repo/grantAgreement/SFI/SFI Advance Award Programme/14/ADV/IA5371/IE/Examination of the cognitive enhancing potential of seaweed-derived mineral-rich nutraceuticals/
dc.relation.urihttp://www.mdpi.com/1660-3397/16/6/216
dc.rights© 2018, the Authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).en
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectMarine extracten
dc.subjectCalciumen
dc.subjectMagnesiumen
dc.subjectGut microbial diversityen
dc.subjectRaten
dc.titleDietary supplementation with a magnesium-rich marine mineral blend enhances the diversity of gastrointestinal microbiotaen
dc.typeArticle (peer-reviewed)en
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