dc.contributor.author	Perry, Ivan J.
dc.contributor.author	Collins, A.
dc.contributor.author	Colwell, N.
dc.contributor.author	Creagh, D.
dc.contributor.author	Drew, C.
dc.contributor.author	Hinchion, Rita
dc.contributor.author	O'Halloran, T. David
dc.contributor.funder	Servier Laboratories (Ireland) Ltd
dc.contributor.funder	Bristol-Myers Squibb, United States
dc.contributor.funder	Pfizer Ireland
dc.contributor.funder	Zeneca Pharma
dc.date.accessioned	2009-10-16T16:03:05Z
dc.date.available	2009-10-16T16:03:05Z
dc.date.issued	2002-11
dc.description.abstract	Contemporary Irish data on the prevalence of major cardiovascular disease (CVD) risk factors are sparse. The primary aims of this study were (1) to estimate the prevalence of major cardiovascular disease risk factors, including Type 2 Diabetes Mellitus, in the general population of men and women between the ages of 50 and 69 years; and (2) to estimate the proportion of individuals in this age group at high absolute risk of cardiovascular disease events on the basis of pre-existing cardiovascular disease or as defined by the Framingham equation. Participants were drawn from the practice lists of 17 general practices in Cork and Kerry using stratified random sampling. A total of 1018 people attended for screening (490 men, 48%) from 1473 who were invited, a response rate of 69.1%. Cardiovascular disease risk factors and glucose intolerance are common in the population of men and women aged between 50 and 69 years. Almost half the participants were overweight and a further quarter met current international criteria for obesity, one of the highest recorded prevalence rates for obesity in a European population sample. Forty per cent of the population reported minimal levels of physical activity and 19% were current cigarette smokers. Approximately half the sample had blood pressure readings consistent with international criteria for the diagnosis of hypertension, but only 38% of these individuals were known to be hypertensive. Eighty per cent of the population sample had a cholesterol concentration in excess of 5 mmol/l. Almost 4% of the population had Type 2 Diabetes Mellitus, of whom 30% were previously undiagnosed. A total of 137 participants (13.5%) had a history or ECG findings consistent with established cardiovascular disease. Of the remaining 881 individuals in the primary prevention population, a total of 20 high-risk individuals (19 male) had a risk of a coronary heart disease event 30% over ten years according to the Framingham risk equation, giving an overall population prevalence of 2.0% (95% CI 1.3 - 3.0). At a risk level 20% over ten years, an additional 91 individuals (8.9%) were identified. Thus a total of 24.4% of the population were at risk either through pre-existing CVD (13.5%) or an estimated 10-year risk exceeding 20% according to the Framingham risk equation (10.9%). Thus a substantial proportion of middle-aged men are at high risk of CVD. The findings emphasise the scale of the CVD epidemic in Ireland and the need for ongoing monitoring of risk factors at the population level and the need to develop preventive strategies at both the clinical and societal level.	en
dc.description.status	Peer reviewed	en
dc.description.version	Published Version	en
dc.format.mimetype	application/pdf	en
dc.format.mimetype	image/gif	en
dc.identifier.citation	Perry I.J., Collins A., Colwell N., Creagh D., D.C., Hinchion R., Neilson S., O'Halloran T.D., 2002. Established cardiovascular disease and CVD risk factors in a primary care population of middle-aged Irish men and women. Irish Medical Journal, 95(10), pp.298-301.	en
dc.identifier.endpage	301	en
dc.identifier.issn	0332-3102
dc.identifier.issued	10	en
dc.identifier.journaltitle	Irish Medical Journal	en
dc.identifier.startpage	298	en
dc.identifier.uri	https://hdl.handle.net/10468/94
dc.identifier.volume	95	en
dc.language.iso	en	en
dc.publisher	Irish Medical Organization	en
dc.relation.uri	http://www.imj.ie//Issue_detail.aspx?issueid=+&pid=63&type=Papers	en
dc.rights	©Irish Medical Journal 2002.	en
dc.subject	Cardiovascular disease risk factors	en
dc.subject	CVD	en
dc.subject	Cardiovascular disesase prevalence	en
dc.subject.lcsh	Heart -- Diseases -- Etiology	en
dc.subject.lcsh	Heart -- Diseases -- Ireland -- Statistics	en
dc.title	Established cardiovascular disease and CVD risk factors in a primary care population of middle-aged Irish men and women	en
dc.type	Article (peer-reviewed)	en

Established cardiovascular disease and CVD risk factors in a primary care population of middle-aged Irish men and women

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