Screening for autistic spectrum disorder at the 18-month developmental assessment: a population-based study

dc.contributor.authorVanDenHeuvel, A.
dc.contributor.authorFitzgerald, M.
dc.contributor.authorGreiner, Birgit A.
dc.contributor.authorPerry, Ivan J.
dc.date.accessioned2009-09-29T14:17:28Z
dc.date.available2009-09-29T14:17:28Z
dc.date.copyright2006
dc.date.issued2007-09
dc.descriptionVanDenHeuvel A, Fitzgerald M, Greiner B, Perry IJ. Screening for autistic spectrum disorder at the 18-month developmental assessment: a population-based study. Ir Med J. 2007;100(8):565-7.en
dc.description.abstractThe objectives of this study were to assess the feasibility of administering the CHecklist for Autism in Toddlers (CHAT) at the 18-month developmental check, estimate the prevalence of screening positive for autism at the first and second administrations of the CHAT and estimate the prevalence of diagnosed cases of autism. A cross-sectional study design was utilised and data was collected at child developmental screening clinics in counties Cork and Kerry. The sample group consisted of infants attending the routine 18-month developmental assessment, who were broadly representative of infants in the catchment area. The main outcome measure was a medium or high-risk score following two administrations of the CHAT screening instrument and a positive diagnosis of autism after clinical assessment. The CHAT was administered to 2117 infants (79% of those approached) of whom 29 were scored at medium or high risk at first screening, resulting in a prevalence rate of 137 per 10,000 (95% CI: 87-187). A total of 7 of the 29 first screen positive infants were positive (medium or high risk) at second screening, 12 were low risk and 10 parents refused to participate. On subsequent clinical assessment of the 7 infants screening positive on first and second assessment and assessment of 5 of the 10 infants whose parents declined second screening, 7 children received a diagnosis of autism. Thus the overall prevalence of clinically diagnosed autism following this screening exercise was 33.1 per 10,000 (95% CI: 13.3 to 68.0). The CHAT instrument is a useful tool to help identify childhood autism among infants. Routine use of this instrument at 18-month developmental assessment merits consideration.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.format.mimetypeimage/jpegen
dc.identifier.citationVanDenHeuvel A., Fitzgerald M., Greiner B., Perry I.J., 2007. Screening for autistic spectrum disorder at the 18-month developmental assessment: a population-based study. Irish Medical Journal, 100(8), pp.565-567.en
dc.identifier.endpage567en
dc.identifier.issn0332-3102
dc.identifier.issued8en
dc.identifier.journaltitleIrish Medical Journalen
dc.identifier.startpage565en
dc.identifier.urihttps://hdl.handle.net/10468/90
dc.identifier.volume100en
dc.language.isoenen
dc.publisherIrish Medical Organizationen
dc.relation.urihttp://imj.ie//Issue_detail.aspx?issueid=+&pid=2500&type=Papers#topen
dc.rights©Irish Medical Journal 2006.en
dc.subjectChecklist for Autism in Toddlers (CHAT)en
dc.subjectAutistic Spectrum Disorderen
dc.subject.lcshAutism in children -- Diagnosisen
dc.subject.lcshAutism in children -- Irelanden
dc.titleScreening for autistic spectrum disorder at the 18-month developmental assessment: a population-based studyen
dc.typeArticle (peer-reviewed)en
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