Early biomarkers of brain injury and cerebral hypo- and hyperoxia in the SafeBoosC II trial

Simple item page
dc.contributor.authorPlomgaard, Anne M.
dc.contributor.authorAlderliesten, Thomas
dc.contributor.authorAustin, Topun
dc.contributor.authorvan Bel, Frank
dc.contributor.authorBenders, Manon
dc.contributor.authorClaris, Olivier
dc.contributor.authorDempsey, Eugene M.
dc.contributor.authorFumagalli, Monica
dc.contributor.authorGluud, Christian
dc.contributor.authorHagmann, Cornelia
dc.contributor.authorHyttel-Sorensen, Simon
dc.contributor.authorLemmers, Petra
dc.contributor.authorvan Oeveren, Wim
dc.contributor.authorPellicer, Adelina
dc.contributor.authorPetersen, Tue H.
dc.contributor.authorPichler, Gerhard
dc.contributor.authorWinkel, Per
dc.contributor.authorGreisen, Gorm
dc.contributor.funderStrategiske Forskningsråd
dc.date.accessioned2017-06-20T11:39:45Z
dc.date.available2017-06-20T11:39:45Z
dc.date.issued2017-03-22
dc.description.abstractThe randomized clinical trial, SafeBoosC II, examined the effect of monitoring of cerebral oxygenation by near-infrared spectroscopy combined with a guideline on treatment when cerebral oxygenation was out of the target range. Data on cerebral oxygenation was collected in both the intervention and the control group. The primary outcome was the reduction in the burden of cerebral hypo- and hyperoxia between the two groups. In this study we describe the associations between the burden of cerebral hypo- and hyperoxia, regardless of allocation to intervention or control group, and the biomarkers of brain injury from birth till term equivalent age that was collected as secondary and explorative outcomes in the SafeBoosC II trial.en
dc.description.sponsorshipStrategiske Forskningsråd (DKK 11,100,105).en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleide0173440
dc.identifier.citationPlomgaard, A. M., Alderliesten, T., Austin, T., van Bel, F., Benders, M., Claris, O., Dempsey, E., Fumagalli, M., Gluud, C., Hagmann, C., Hyttel-Sorensen, S., Lemmers, P., van Oeveren, W., Pellicer, A., Petersen, T. H., Pichler, G., Winkel, P. and Greisen, G. (2017) 'Early biomarkers of brain injury and cerebral hypo- and hyperoxia in the SafeBoosC II trial', PLoS ONE, 12(3), e0173440 (15pp). doi: 10.1371/journal.pone.0173440en
dc.identifier.doi10.1371/journal.pone.0173440
dc.identifier.endpage15
dc.identifier.issn1932-6203
dc.identifier.issued3
dc.identifier.journaltitlePLOS ONEen
dc.identifier.startpage1
dc.identifier.urihttps://hdl.handle.net/10468/4108
dc.identifier.volume12
dc.language.isoenen
dc.publisherPLoSen
dc.relation.urihttp://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173440
dc.rights© 2017, Plomgaard et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectBrain damageen
dc.subjectHyperoxiaen
dc.subjectMedical hypoxiaen
dc.subjectBiomarkersen
dc.subjectElectroencephalographyen
dc.subjectInfantsen
dc.subjectNear-infrared spectroscopyen
dc.subjectHemorrhageen
dc.subject~Paediatrics and Child Health - Journal Articles~en
dc.titleEarly biomarkers of brain injury and cerebral hypo- and hyperoxia in the SafeBoosC II trialen
dc.typeArticle (peer-reviewed)en
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
2764.pdf
Size:
1.64 MB
Format:
Adobe Portable Document Format
Description:
Published Version
Download
Collections
INFANT Research Centre - Journal Articles
School of Medicine