Pushing past the tipping points in containment trajectories of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemics: A simple arithmetic rationale for crushing the curve instead of merely flattening it

dc.contributor.authorKilleen, Gerry F.
dc.contributor.funderAXA Research Funden
dc.date.accessioned2020-07-01T15:32:13Z
dc.date.available2020-07-01T15:32:13Z
dc.date.issued2020-06-30
dc.date.updated2020-07-01T15:24:59Z
dc.description.abstractCountries with ambitious national strategies to crush the curve of their Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) epidemic trajectories include China, Korea, Japan, Taiwan, New Zealand and Australia. However, the United States and many hard-hit European countries, like Ireland, Italy, Spain, France and the United Kingdom, currently appear content to merely flatten the curve of their epidemic trajectories so that transmission persists at rates their critical care services can cope with. Here I present a simple set of arithmetic modelling analyses that are accessible to non-specialists and explain why preferable crush the curve strategies, to eliminate transmission within months, would require only a modest amount of additional containment effort relative to the tipping point targeted by flatten the curve strategies, which allow epidemics to persist at supposedly steady, manageable levels for years, decades or even indefinitely.en
dc.description.sponsorshipAXA Research Fund (Research Chair award)en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationKilleen, G. F. (2020) 'Pushing past the tipping points in containment trajectories of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemics: A simple arithmetic rationale for crushing the curve instead of merely flattening it', Infectious Disease Modelling, In Press, doi: 10.1016/j.idm.2020.06.001en
dc.identifier.doi10.1016/j.idm.2020.06.001en
dc.identifier.endpage13en
dc.identifier.issn2468-0427
dc.identifier.journaltitleInfectious Disease Modellingen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/10192
dc.language.isoenen
dc.publisherElsevieren
dc.relation.urihttp://www.sciencedirect.com/science/article/pii/S2468042720300178
dc.rights© 2020 The Authors. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co.,Ltd. Open Access, Under a Creative Commons license https://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/en
dc.subjectCoronavirusen
dc.subjectCOVIDen
dc.subjectSARS2en
dc.subjectSevere acute respiratory syndrome coronavirus 2en
dc.subjectSARS-CoV-2en
dc.subjectModelen
dc.subjectEpidemiologyen
dc.subjectOutbreaken
dc.subjectZoonosisen
dc.subjectEmerging infectionen
dc.titlePushing past the tipping points in containment trajectories of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemics: A simple arithmetic rationale for crushing the curve instead of merely flattening iten
dc.typeArticle (peer-reviewed)en
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