Bifidobacterial transfer from mother to child as examined by an animal model

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dc.contributor.authorMancino, Walter
dc.contributor.authorDuranti, Sabrina
dc.contributor.authorMancabelli, Leonardo
dc.contributor.authorLonghi, Giulia
dc.contributor.authorAnzalone, Rosaria
dc.contributor.authorMilani, Christian
dc.contributor.authorLugli, Gabriele Andrea
dc.contributor.authorCarnevali, Luca
dc.contributor.authorStatello, Rosario
dc.contributor.authorSgoifo, Andrea
dc.contributor.authorvan Sinderen, Douwe
dc.contributor.authorVentura, Marco
dc.contributor.authorTurroni, Francesca
dc.contributor.funderJoint Programming Initiative Urban Europeen
dc.contributor.funderScience Foundation Irelanden
dc.contributor.funderMinistero dell’Istruzione, dell’Università e della Ricercaen
dc.contributor.funderFondazione Cariparmaen
dc.date.accessioned2019-10-14T21:24:24Z
dc.date.available2019-10-14T21:24:24Z
dc.date.issued2019-08-27
dc.description.abstractBifidobacteria commonly constitute the most abundant group of microorganisms in the healthy infant gut. Their intestinal establishment is believed to be maternally driven, and their acquisition has even been postulated to occur during pregnancy. In the current study, we evaluated bifidobacterial mother-to infant transmission events in a rat model by means of quantitative PCR (qPCR), as well as by Internally Transcribed Spacer (ITS) bifidobacterial profiling. The occurrence of strains supplied by mothers during pregnancy to their corresponding newborns was observed and identified by analysis immediately following C-section delivery. These findings provide intriguing support for the existence of an unknown route to facilitate bifidobacterial transfer during the very early stages of life.en
dc.description.sponsorshipScience Foundation Ireland (SFI) (Grant number 15/JP-HDHL/3280, SFI/12/RC/2273-P1 and SFI/12/RC/2273-P2); Fondazione Cariparma (TeachInParma Project)en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.articleid293en
dc.identifier.citationMancino, W., Duranti, S., Mancabelli, L., Longhi, G., Anzalone, R., Milani, C., Lugli, G. A., Carnevali, L., Statello, R., Sgoifo, A., van Sinderen, D., Ventura, M. and Turroni, F. (2019) 'Bifidobacterial Transfer from Mother to Child as Examined by an Animal Model', Microorganisms, 7(9), 293 (13pp.). DOI: 10.3390/microorganisms7090293en
dc.identifier.doi10.3390/microorganisms7090293en
dc.identifier.eissn2076-2607
dc.identifier.endpage13en
dc.identifier.issued9en
dc.identifier.journaltitleMicroorganismsen
dc.identifier.startpage1en
dc.identifier.urihttps://hdl.handle.net/10468/8749
dc.identifier.volume7en
dc.language.isoenen
dc.publisherMDPIen
dc.relation.urihttps://www.mdpi.com/2076-2607/7/9/293/htm
dc.rights© The Author(s) 2019. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly citeden
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en
dc.subjectBifidobacteriaen
dc.subjectInfant gut microbiotaen
dc.subjectMicrobe-host coevolutionen
dc.subjectMetagenomicsen
dc.titleBifidobacterial transfer from mother to child as examined by an animal modelen
dc.typeArticle (peer-reviewed)en
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