Non-invasive assessment of cartilage damage of the human knee using acoustic emission monitoring: A pilot cadaver study

Loading...
Thumbnail Image
Date
2023-03-30
Authors
Khokhlova, Liudmila
Komaris, Dimitrios-Sokratis
Davarinos, Nikolaos
Mahalingam, Karuppiah
O'Flynn, Brendan
Tedesco, Salvatore
Journal Title
Journal ISSN
Volume Title
Publisher
Institute of Electrical and Electronics Engineers (IEEE)
Research Projects
Organizational Units
Journal Issue
Abstract
Objective: Knee osteoarthritis is currently one of the top causes of disability in older population, a rate that will only increase in the future due to an aging population and the prevalence of obesity. However, objective assessment of treatment outcomes and remote evaluation are still in need of further development. Acoustic emission (AE) monitoring in knee diagnostics has been successfully adopted in the past; however, a wide discrepancy among the adopted AE techniques and analyses exists. This pilot study determined the most suitable metrics to differentiate progressive cartilage damage and the optimal frequency range and placement of AE sensors. Methods: Knee AEs were recorded in the 100–450 kHz and 15–200kH frequency ranges from a cadaver specimen in knee flexion/extension. Four stages of artificially inflicted cartilage damage and two sensor positions were investigated. Results: AE events in the lower frequency range and the following parameters provided better distinction between intact and damaged knee: hit amplitude, signal strength, and absolute energy. The medial condyle area of the knee was less prone to artefacts and unsystematic noise. Multiple reopenings of the knee compartment in the process of introducing the damage negatively affected the quality of the measurements. Conclusion: Results may improve AE recording techniques in future cadaveric and clinical studies. Significance: This was the first study to evaluate progressive cartilage damage using AEs in a cadaver specimen. The findings of this study encourage further investigation of joint AE monitoring techniques.
Description
Keywords
Acoustic emission , Joint sound , Knee health , Osteoarthritis , Thinning of the articular cartilage
Citation
Khokhlova, L., Komaris, D. -S., Davarinos, N., Mahalingam, K., O'Flynn, B. and Tedesco, S. (2023) 'Non-invasive assessment of cartilage damage of the human knee using acoustic emission monitoring: A pilot cadaver study', IEEE Transactions on Biomedical Engineering, 70(9), pp. 2741-2751. doi: 10.1109/TBME.2023.3263388