dc.contributor.author	Buttimer, Colin
dc.contributor.author	Hendrix, Hanne
dc.contributor.author	Oliveira, Hugo
dc.contributor.author	Casey, Aidan
dc.contributor.author	Neve, Horst
dc.contributor.author	McAuliffe, Olivia
dc.contributor.author	Ross, R. Paul
dc.contributor.author	Hill, Colin
dc.contributor.author	Noben, Jean-Paul
dc.contributor.author	O'Mahony, Jim
dc.contributor.author	Lavigne, Rob
dc.contributor.author	Coffey, Aidan
dc.contributor.funder	Cork Institute of Technology	en
dc.contributor.funder	KU Leuven	en
dc.date.accessioned	2017-02-24T19:40:17Z
dc.date.available	2017-02-24T19:40:17Z
dc.date.issued	2017-01-24
dc.date.updated	2017-02-24T19:22:48Z
dc.description.abstract	Enterobacteria phage vB_PcaM_CBB is a “jumbo” phage belonging to the family Myoviridae. It possesses highly atypical whisker-like structures along the length of its contractile tail. It has a broad host range with the capability of infecting species of the genera Erwinia, Pectobacterium, and Cronobacter. With a genome of 355,922 bp, excluding a predicted terminal repeat of 22,456 bp, phage CBB is the third largest phage sequenced to date. Its genome was predicted to encode 554 ORFs with 33 tRNAs. Based on prediction and proteome analysis of the virions, 29% of its predicted ORFs could be functionally assigned. Protein comparison shows that CBB shares between 33–38% of its proteins with Cronobacter phage GAP32, coliphages PBECO4 and 121Q as well as Klebsiella phage vB_KleM_Rak2. This work presents a detailed and comparative analysis of vB_PcaM_CBB of a highly atypical jumbo myoviridae phage, contributing to a better understanding of phage diversity and biology.	en
dc.description.sponsorship	Cork Institute of Technology (Project Reference 2012BIOL); KU Leuven (Geconcerteerde Onderzoeks Actie grant “Phage Biosystems”)	en
dc.description.status	Peer reviewed	en
dc.description.version	Published Version	en
dc.format.mimetype	application/pdf	en
dc.identifier.articleid	44
dc.identifier.citation	Buttimer, C., Hendrix, H., Oliveira, H., Casey, A., Neve, H., McAuliffe, O., Ross, R. P., Hill, C., Noben, J.-P., O’Mahony, J., Lavigne, R. and Coffey, A. (2017) 'Things are getting hairy: Enterobacteria bacteriophage vB_PcaM_CBB', Frontiers In Microbiology, 8, 44 (16pp). doi:10.3389/fmicb.2017.00044	en
dc.identifier.doi	10.3389/fmicb.2017.00044
dc.identifier.endpage	16	en
dc.identifier.issn	1664-302X
dc.identifier.journaltitle	Frontiers In Microbiology	en
dc.identifier.startpage	1	en
dc.identifier.uri	https://hdl.handle.net/10468/3694
dc.identifier.volume	8	en
dc.language.iso	en	en
dc.publisher	Frontiers Media	en
dc.rights	© 2017, the Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.	en
dc.rights.uri	https://creativecommons.org/licenses/by/4.0/	en
dc.subject	Bacteriophages	en
dc.subject	Genome	en
dc.subject	Bioinformatics	en
dc.subject	Mass spectrometry	en
dc.subject	Jumbo bacteriophage	en
dc.subject	PFGE analysis	en
dc.subject	Host range	en
dc.subject	Transmission electron microscopy	en
dc.title	Things are getting hairy: Enterobacteria bacteriophage vB_PcaM_CBB	en
dc.type	Article (peer-reviewed)	en

Things are getting hairy: Enterobacteria bacteriophage vB_PcaM_CBB

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