The maternal and perinatal implications of hypertensive disorders of pregnancy in a multiple pregnancy cohort

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dc.check.date2020-11-23
dc.check.infoAccess to this article is restricted until 12 months after publication by request of the publisher.en
dc.contributor.authorHayes-Ryan, Deirdre
dc.contributor.authorMeaney, Sarah
dc.contributor.authorHodnett, Aoibhin
dc.contributor.authorGeisler, Minna
dc.contributor.authorO'Donoghue, Keelin
dc.date.accessioned2019-12-03T12:08:00Z
dc.date.available2019-12-03T12:08:00Z
dc.date.issued2019-11-23
dc.date.updated2019-12-03T11:51:15Z
dc.description.abstractIntroduction: Hypertensive Disorders of Pregnancy are common and may result in increased maternal and neonatal morbidity and mortality. Multiple pregnancies confer an increased risk of development of a hypertensive disorder of pregnancy. The purpose of this study was to examine a large cohort of women delivering a multiple pregnancy in a single large tertiary unit, and to evaluate the implications of hypertensive disorders of pregnancy on both maternal and perinatal outcomes. Material and methods: Retrospective study of all twin pregnancies delivered at Cork University Maternity Hospital, Ireland over a 9‐year period (2009–2017). The twin pregnancies were divided according to the presence or absence of hypertensive disorder of pregnancy and the two groups compared. Results: Maternal age >40 years, nulliparity, conception through use of a donor oocyte, and presence of obstetric cholestasis are all risk factors for the development of Hypertensive Disorders of Pregnancy in women with a multiple pregnancy. When a hypertensive disorder complicates a twin pregnancy, it increases the incidence of iatrogenic late prematurity & neonatal hypoglycaemia. Conclusions: This study is informative for clinicians caring for women with a multiple pregnancy with its relevant data on perinatal outcomes following a diagnosis of hypertensive disorder in pregnancy.en
dc.description.statusPeer revieweden
dc.description.versionAccepted Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationHayes-Ryan, D., Meaney, S., Hodnett, A., Geisler, M. and O'Donoghue, K. (2019) 'The maternal and perinatal implications of hypertensive disorders of pregnancy in a multiple pregnancy cohort', Acta Obstetricia et Gynecologica Scandinavica. doi: 10.1111/aogs.13774en
dc.identifier.doi10.1111/aogs.13774en
dc.identifier.eissn1600-0412
dc.identifier.issn0001-6349
dc.identifier.journaltitleActa Obstetricia et Gynecologica Scandinavicaen
dc.identifier.urihttps://hdl.handle.net/10468/9300
dc.language.isoenen
dc.publisherJohn Wiley & Sons, Inc.en
dc.relation.urihttps://obgyn.onlinelibrary.wiley.com/doi/abs/10.1111/aogs.13774
dc.rights© 2019, Nordic Federation of Societies of Obstetrics and Gynecology. Published by John Wiley & Sons Inc. This is the peer reviewed version of the following article: Hayes-Ryan, D., Meaney, S., Hodnett, A., Geisler, M. and O'Donoghue, K. (2019) 'The maternal and perinatal implications of hypertensive disorders of pregnancy in a multiple pregnancy cohort', Acta Obstetricia et Gynecologica Scandinavica, doi: 10.1111/aogs.13774, which has been published in final form at https://doi.org/10.1111/aogs.13774. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.en
dc.subjectGestational hypertensionen
dc.subjectHypertensive disorder of pregnancyen
dc.subjectMultiple pregnancyen
dc.subjectTwin pregnancyen
dc.subjectPre-eclampsiaen
dc.titleThe maternal and perinatal implications of hypertensive disorders of pregnancy in a multiple pregnancy cohorten
dc.typeArticle (peer-reviewed)en
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