Prevalence and lifestyle determinants of the metabolic syndrome

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dc.contributor.authorVillegas, Raquel
dc.contributor.authorCreagh, D.
dc.contributor.authorHinchion, Rita
dc.contributor.authorO'Halloran, D.
dc.contributor.authorPerry, Ivan J.
dc.date.accessioned2009-10-15T16:28:06Z
dc.date.available2009-10-15T16:28:06Z
dc.date.copyright2004
dc.date.issued2004-11
dc.description.abstractParticipants with the metabolic syndrome are at risk of developing type 2 diabetes and coronary heart disease. The aim of this study was to determine the role of lifestyle risk factors in the development of the metabolic syndrome with particular reference to physical activity, smoking and alcohol consumption. We performed a cross sectional study of the prevalence of CVD risk factors and glucose intolerance, including type 2 diabetes involving a group of 1473 men and women were sampled from 17 general practice lists in the South of Ireland. A total of 1018 attended for screening, giving a response rate of 69%. Participants completed a detailed health and lifestyle questionnaire and provided fasting blood samples for analysis of glucose, insulin and lipids. The metabolic syndrome was defined according to the current WHO criteria. The prevalence of the metabolic syndrome was 21.0% (95% C.I. 18.7% to 24.1%). In multivariate analyses with the metabolic syndrome as the dependent variable we observed a significant, independent inverse association with physical activity level (OR=0.60; 95%CI, 0.39-0.90 for medium and OR=0.51; 95%CI, 0.28-0.93) for high level of activity relative to the low level of activity group). Ex-drinkers had a higher prevalence of the syndrome in multivariate analysis relative to occasional drinkers, (OR=2.38; 95%CI, 1.08-5.26). Prevalence of the metabolic syndrome was not significantly associated with current alcohol consumption or with smoking status. These data highlight the importance of physical inactivity in the aetiology of the metabolic syndrome.en
dc.description.statusPeer revieweden
dc.description.versionPublished Versionen
dc.format.mimetypeapplication/pdfen
dc.identifier.citationVillegas R., Creagh D., Hinchion R., O’Halloran D., Perry I.J., 2004. Prevalence and lifestyle determinants of the metabolic syndrome. Irish Medical Journal, 97(10), pp.300-303.en
dc.identifier.endpage303en
dc.identifier.issn0332-3102
dc.identifier.issued10en
dc.identifier.journaltitleIrish Medical Journalen
dc.identifier.startpage300en
dc.identifier.urihttps://hdl.handle.net/10468/93
dc.identifier.volume97en
dc.language.isoenen
dc.publisherIrish Medical Organizationen
dc.relation.urihttp://www.imj.ie//Issue_detail.aspx?issueid=+&pid=348&type=Papers
dc.rights©Irish Medical Journal 2004en
dc.subjectLifestyle risk factorsen
dc.subjectMetabolic syndrome prevalenceen
dc.subject.lcshMetabolic syndrome -- Etiologyen
dc.subject.lcshMetabolic syndrome -- Statistics -- Irelanden
dc.subject.lcshDiabetes -- Etiologyen
dc.subject.lcshHealth behavioren
dc.titlePrevalence and lifestyle determinants of the metabolic syndromeen
dc.typeArticle (peer-reviewed)en
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