Increasing objectivity in quantitative analysis in immune-histochemistry biomarker mapping using upconverting nanoparticles

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omp-2025-otu1e.2.pdf(391.71 KB)
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Date
2025-04
Authors
Mickert, Matthias
Helgstrand, Magnus
Konugolu Venkata Sekar, Sanathana
Ma, Hui
Komolibus, Katarzyna
Kho, Kiang Wei
Johansson, Andreas
Wallenborg, Sanna
Andersson-Engels, Stefan
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Publisher
Optica Publishing Group
Published Version
10.1364/omp.2025.otu1e.2
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Abstract
Today immunohistochemistry (IHC) stains molecular biomarkers for treatment stratification. IHC can become increasingly objective by improving sensitivity, quantification and multiplexing capabilities. We use upconverting nanoparticles to achieve this, potentially leading to improved treatment outcomes.
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Keywords
Immunohistochemistry (IHC) , Upconverting nanoparticles
Citation
Mickert, M., Helgstrand, M., Sekar, S. K. V., Ma, H., Komolibus, K., Kho, K. W., Johansson, A., Wallenborg, S. and Andersson-Engels, S. (2025) 'Increasing objectivity in quantitative analysis in immune-histochemistry biomarker mapping using upconverting nanoparticles', Optica Biophotonics Congress 2025, Technical Digest Series, paper OTu1E.2 (2pp). https://doi.org/10.1364/OMP.2025.OTu1E.2
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https://hdl.handle.net/10468/17798
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Tyndall National Institute - Conference Items
Physics - Conference Items
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© 2025, the Authors. Published by Optica Publishing Group.